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NCT05134857 · ClinicalTrials.gov registry record · Phase 2
The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study
A Phase 2 study of Alcohol Use Disorder (AUD), sponsored by Washington State University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 205
- Enrollment target
- 1
- Study location
NCT05134857: Recruiting Phase 2 study of Alcohol Use Disorder (AUD), sponsored by Washington State University.
NCT05134857 is a Phase 2 study of Alcohol Use Disorder (AUD) that is actively recruiting participants, run by Washington State University. The registered enrollment target is 205 participants, below the 1,817-participant average among 30 other Alcohol Use Disorder (AUD) trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05134857, a Phase 2 study of Alcohol Use Disorder (AUD), is actively recruiting participants, sponsored by Washington State University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 205 participants
- Enrollment target
- 1
- Study location
Study Summary
A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).
Primary Outcome
Consumption of alcohol between participants randomized to ZON+ST vs PLO+ST assessed by participant self report (collected 1x weekly from weeks 1-14 and once at weeks 18, 38, and 54).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Zonisamide
Study Locations (1)
Washington
- Washington State University - Spokane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 205 participants |
| Start Date | 2022-01-07 |
| Est. Completion | 2026-08-31 |
| Phase | Phase 2 |
What NCT05134857 shows while recruiting
NCT05134857 is an interventional study that assigns participants to a tested intervention. The registered 205 participants enrollment target is mid-sized for trials with a published cap, below the 1,817-participant average among 30 other Alcohol Use Disorder (AUD) trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Alcohol Use Disorder (AUD) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05134857 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT05134857 about?
NCT05134857 is a clinical study titled "The Zonisamide and Reinforcement for Reducing Alcohol Use (ZARRA) Study". A phase II randomized, double-blind, placebo-controlled clinical trial (RCT) to evaluate the ability of zonisamide (ZON) to decrease alcohol use among treatment-seeking adults with an alcohol use disorder (AUD).
What is the current status of trial NCT05134857?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 205 participants. The study started on 2022-01-07. Estimated completion is 2026-08-31.
What conditions does trial NCT05134857 study?
This clinical trial studies the following conditions: Alcohol Use Disorder (AUD).
What interventions are being tested in trial NCT05134857?
The interventions under investigation include: Placebo (DRUG), Zonisamide (DRUG).
Who is sponsoring clinical trial NCT05134857?
This trial is sponsored by Washington State University, which has 64 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05134857 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Use Disorder (AUD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05134857's enrollment target sits among peer trials
205 5th of 30 higher than 25 of 30 other Alcohol Use Disorder (AUD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Use Disorder (AUD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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