Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 12 recruiting now official registry

Acute Myeloid Leukemia, in Relapse clinical trials

12 of 17 indexed Acute Myeloid Leukemia, in Relapse trials are currently recruiting.

17 US clinical trials · 12 currently recruiting

Acute Myeloid Leukemia, in Relapse is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 2 of these trials.

The research picture

Acute Myeloid Leukemia, in Relapse has 17 registered US clinical trials, 12 of them open to new participants right now, about 71% of the total.

12
recruiting participants now
71%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 116Phase 21

Active & Recent Trials

17 total, page 1 of 1

RECRUITING Phase 1 420 participants

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Kura Oncology

NCT05735184

RECRUITING Phase 1 78 participants

AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

AB Science

NCT05211570

RECRUITING Phase 1 50 participants

Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)

Oryzon Genomics S.A.

NCT05546580

RECRUITING Phase 1 49 participants

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

ARCE Therapeutics

NCT06680752

RECRUITING Phase 1 48 participants

A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)

Bio-Path Holdings

NCT05190471

RECRUITING Phase 1 40 participants

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

Marker Therapeutics

NCT06552416

RECRUITING Phase 1 40 participants

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Medical College of Wisconsin

NCT05317403

RECRUITING Phase 1 18 participants

A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

Memorial Sloan Kettering Cancer Center

NCT07011004

RECRUITING Phase 1 18 participants

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

Seattle Children's Hospital

NCT05105152

RECRUITING Phase 1 18 participants

Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Terrence J Bradley, MD

NCT05597306

RECRUITING Phase 1 15 participants

A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid Leukemia

Memorial Sloan Kettering Cancer Center

NCT06017258

RECRUITING Phase 1 15 participants

Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Keystone Nano

NCT04716452

ACTIVE NOT RECRUITING Phase 1 37 participants

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

St. Jude Children's Research Hospital

NCT04898894

ACTIVE NOT RECRUITING Phase 1 33 participants

A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Beth Israel Deaconess Medical Center

NCT02204085

ACTIVE NOT RECRUITING Phase 1 22 participants

Lentivirally Redirected CD123 Autologous T Cells in AML

University of Pennsylvania

NCT03766126

COMPLETED Phase 2 38 participants

High Dose Cytarabine Followed by Pembrolizumab in Relapsed/Refractory AML

UNC Lineberger Comprehensive Cancer Center

NCT02768792

COMPLETED Phase 1 16 participants

KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia

University of Colorado, Denver

NCT04914845

Phase Distribution

PhaseTrial count
Phase 1 16
Phase 2 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Myeloid Leukemia, in Relapse Trial Landscape

17 indexed Acute Myeloid Leukemia, in Relapse studies · 12 recruiting (71%).

Phase mix: 0 late (III/IV) vs 17 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (2 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Myeloid Leukemia, in Relapse?

PlainTrial tracks 17 US clinical trials for Acute Myeloid Leukemia, in Relapse, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Myeloid Leukemia, in Relapse?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.