Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00645918 · ClinicalTrials.gov registry record · NA
GRAVITAS: Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety
A NA study of Acute Coronary Syndrome and Coronary Arteriosclerosis, sponsored by Accumetrics.
- Completed
- Registry status
- NA
- Development phase
- 2,800
- Enrollment target
- 20
- Study locations
NCT00645918: Completed NA study of Acute Coronary Syndrome and Coronary Arteriosclerosis, sponsored by Accumetrics.
NCT00645918 is a NA study of Acute Coronary Syndrome and Coronary Arteriosclerosis that has completed, run by Accumetrics. The registered enrollment target is 2,800 participants, roughly in line with the 2,652-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target. The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00645918, a NA study of Acute Coronary Syndrome and Coronary Arteriosclerosis, has completed, sponsored by Accumetrics.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,800 participants
- Enrollment target
- 20
- Study locations
Study Summary
The objective of the GRAVITAS trial is to determine whether tailored anti-platelet therapy using the Accumetrics VerifyNow P2Y12 assay reduces major adverse cardiovascular events after drug-eluting stent implantation.
Conditions Studied
Interventions
- DRUG placebo
- DRUG clopidogrel
Study Locations (20)
California
- Scripps Green Hospital - La Jolla
- El Camino Hospital - Mountain View
- UC Davis Medical Center - Sacramento
- Sacramento Heart and Vascular Research Center - Sacramento
- UCSD Medical Center - San Diego
- Alvarado Hospital - San Diego
- San Francisco General Hospital - San Francisco
- UCSF Moffitt-Long Hospital - San Francisco
- Santa Barbara Cottage Hospital - Santa Barbara
- Torrance Memorial Medical Center - Torrance
Florida
- Clearwater Cardiovascular and Interventional Consultants - Clearwater
- University of Florida Health Science Center - Jacksonville
- Cardiology Research Associates - Ormond Beach
Arizona
- Scottsdale Health Care - Osborn Campus - Scottsdale
- Scottsdale Health Care - Shea Campus - Scottsdale
Connecticut
- Bridgeport Hospital - Bridgeport
- Danbury Hospital - Danbury
Alabama
- University of Alabama at Birmingham - Birmingham
Delaware
- Christiana Care Hospital - Newark
District of Columbia
- Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,800 participants |
| Start Date | 2008-06 |
| Est. Completion | 2010-10 |
| Phase | NA |
What the finished NCT00645918 record still lists
NCT00645918 is an interventional study that assigns participants to a tested intervention. Its 2,800 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 2,652-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target.
The record links to 2 conditions, with Acute Coronary Syndrome appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT00645918 names 20 study sites across 7 states, led by California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT00645918 about?
NCT00645918 is a clinical study titled "GRAVITAS: Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety". The objective of the GRAVITAS trial is to determine whether tailored anti-platelet therapy using the Accumetrics VerifyNow P2Y12 assay reduces major adverse cardiovascular events after drug-eluting stent implantation.
What is the current status of trial NCT00645918?
This trial is currently completed. It is a NA study. The enrollment target is 2,800 participants. The study started on 2008-06. Estimated completion is 2010-10.
What conditions does trial NCT00645918 study?
This clinical trial studies the following conditions: Acute Coronary Syndrome, Coronary Arteriosclerosis.
What interventions are being tested in trial NCT00645918?
The interventions under investigation include: placebo (DRUG), clopidogrel (DRUG).
Who is sponsoring clinical trial NCT00645918?
This trial is sponsored by Accumetrics, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00645918 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Coronary Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00645918's enrollment target sits among peer trials
2,800 8th of 40 higher than 33 of 40 other Acute Coronary Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Coronary Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Positive Emotions Following Acute Cardiac Events
RECRUITING · NA
-
Healthy Heart Habits-2
ACTIVE NOT RECRUITING · NA
-
LEADERS FREE II: BioFreedom™ Pivotal Study
ACTIVE NOT RECRUITING · NA
-
OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
ACTIVE NOT RECRUITING · NA
-
Post Acute Cardiac Event Smoking (PACES) Study
ACTIVE NOT RECRUITING · NA
-
Cost Comparison of Cardiac Magnetic Resonance Imaging (MRI) Use in Emergency Department (ED) Patients With Chest Pain
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05443737 · 2,800 participants · Phase 3
Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients
- NCT05899439 · 2,800 participants
Immune Function and the Progression to T1D
- NCT06089109 · 2,800 participants · NA
Creating VIP Corps to Reduce Maternal Deaths
- NCT06345339 · 2,800 participants · Phase 2
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia