Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome

NCT04873934 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to study the effectiveness of implementation of a systematic LDL-C management pathway including treatment with inclisiran in participants who have experienced a recent acute coronary syndrome (ACS) and have an increased LDL-cholesterol (≥70 mg/dL) despite being treated with a statin drug.

Conditions Studied

Interventions

  • DRUG Inclisiran

Study Locations (20)

California

  • Central Cardiology Medical Center — Bakersfield
  • The Heart Group Cardiovascular Associates Inc — Fresno
  • Mission Heritage Medical Group — Mission Viejo
  • Northbay Clinical Research LLC — Santa Rosa
  • Clinnova Research Solutions — Torrance
  • Harbor-UCLA Medical Center — Torrance
  • Interv Cardiology Med Grp — West Hills

Florida

  • Nova Clinical Research LLC — Bradenton
  • Teradan Clinical trials LLC — Brandon
  • Clearwater Cardiovascular and Interventional Consultants — Clearwater
  • Cardiology Research Associates — Daytona Beach
  • Holy Cross Hospital Inc — Fort Lauderdale
  • Baptist Health Research Institute — Jacksonville

Colorado

  • Aurora Denver Cardiology Associates — Aurora
  • Colorado Springs Cardiology — Colorado Springs
  • Colorado Heart and Vascular — Lakewood

District of Columbia

  • Washington Hospital Center — Washington D.C.
  • George Washington Univ Medical Ctr — Washington D.C.

Arkansas

  • Northeast Arkansas Baptist Clinic — Jonesboro

Connecticut

  • Cardiology Ass of Fairfield County — Stamford

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2021-06-24
Est. Completion 2024-08-07
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

792 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04873934

The ClinicalTrials.gov registry entry for NCT04873934 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Acute Coronary Syndrome appearing as the primary indexed condition, and to 1 intervention — of which Inclisiran is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04873934 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04873934 about?

NCT04873934 is a clinical study titled "Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome". The purpose of this study is to study the effectiveness of implementation of a systematic LDL-C management pathway including treatment with inclisiran in participants who have experienced a recent acute coronary syndrome (ACS) and have an increased LDL-cholesterol (≥70 mg/dL) despite being treated w...

What is the current status of trial NCT04873934?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 400 participants. The study started on 2021-06-24. Estimated completion is 2024-08-07.

What conditions does trial NCT04873934 study?

This clinical trial studies the following conditions: Acute Coronary Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04873934?

The interventions under investigation include: Inclisiran (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04873934?

This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04873934 being conducted?

This trial has 20 study locations across Arkansas, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial