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NCT04873934 · ClinicalTrials.gov registry record · Phase 3
Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome
A Phase 3 study of Acute Coronary Syndrome, sponsored by Novartis Pharmaceuticals.
- Completed
- Registry status
- Phase 3
- Development phase
- 400
- Enrollment target
- 20
- Study locations
NCT04873934: Completed Phase 3 study of Acute Coronary Syndrome, sponsored by Novartis Pharmaceuticals.
NCT04873934 is a Phase 3 study of Acute Coronary Syndrome that has completed, run by Novartis Pharmaceuticals. The registered enrollment target is 400 participants, below the 2,712-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target (85% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04873934, a Phase 3 study of Acute Coronary Syndrome, has completed, sponsored by Novartis Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 400 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to study the effectiveness of implementation of a systematic LDL-C management pathway including treatment with inclisiran in participants who have experienced a recent acute coronary syndrome (ACS) and have an increased LDL-cholesterol (≥70 mg/dL) despite being treated with a statin drug.
Primary Outcome
Percent change from baseline in Low-Density Lipoprotein Cholesterol (LDL-C) at Day 330
Conditions Studied
Interventions
- DRUG Inclisiran
Study Locations (20)
California
- Central Cardiology Medical Center - Bakersfield
- The Heart Group Cardiovascular Associates Inc - Fresno
- Mission Heritage Medical Group - Mission Viejo
- Northbay Clinical Research LLC - Santa Rosa
- Clinnova Research Solutions - Torrance
- Harbor-UCLA Medical Center - Torrance
- Interv Cardiology Med Grp - West Hills
Florida
- Nova Clinical Research LLC - Bradenton
- Teradan Clinical trials LLC - Brandon
- Clearwater Cardiovascular and Interventional Consultants - Clearwater
- Cardiology Research Associates - Daytona Beach
- Holy Cross Hospital Inc - Fort Lauderdale
- Baptist Health Research Institute - Jacksonville
Colorado
- Aurora Denver Cardiology Associates - Aurora
- Colorado Springs Cardiology - Colorado Springs
- Colorado Heart and Vascular - Lakewood
District of Columbia
- Washington Hospital Center - Washington D.C.
- George Washington Univ Medical Ctr - Washington D.C.
Arkansas
- Northeast Arkansas Baptist Clinic - Jonesboro
Connecticut
- Cardiology Ass of Fairfield County - Stamford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2021-06-24 |
| Est. Completion | 2024-08-07 |
| Phase | Phase 3 |
What the finished NCT04873934 record still lists
NCT04873934 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 2,712-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Acute Coronary Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Inclisiran is the first listed.
NCT04873934 names 20 study sites across 6 states, led by California, Florida, Colorado.
Frequently Asked Questions
What is clinical trial NCT04873934 about?
NCT04873934 is a clinical study titled "Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome". The purpose of this study is to study the effectiveness of implementation of a systematic LDL-C management pathway including treatment with inclisiran in participants who have experienced a recent acute coronary syndrome (ACS) and have an increased LDL-cholesterol (≥70 mg/dL) despite being treated w...
What is the current status of trial NCT04873934?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 400 participants. The study started on 2021-06-24. Estimated completion is 2024-08-07.
What conditions does trial NCT04873934 study?
This clinical trial studies the following conditions: Acute Coronary Syndrome.
What interventions are being tested in trial NCT04873934?
The interventions under investigation include: Inclisiran (DRUG).
Who is sponsoring clinical trial NCT04873934?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04873934 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, Connecticut, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Coronary Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04873934's enrollment target sits among peer trials
400 22nd of 40 higher than 19 of 40 other Acute Coronary Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Coronary Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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