Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03413423 · ClinicalTrials.gov registry record · NA
Post Acute Cardiac Event Smoking (PACES) Study
A NA study of Tobacco Use and Acute Coronary Syndrome, sponsored by Hennepin Healthcare Research Institute.
- Active
- Registry status
- NA
- Development phase
- 233
- Enrollment target
- 1
- Study location
NCT03413423: Active NA study of Tobacco Use and Acute Coronary Syndrome, sponsored by Hennepin Healthcare Research Institute.
NCT03413423 is a NA study of Tobacco Use and Acute Coronary Syndrome that is active but no longer recruiting, run by Hennepin Healthcare Research Institute. The registered enrollment target is 233 participants, below the 376-participant average among 76 other Tobacco Use trials with a reported enrollment target (38% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03413423, a NA study of Tobacco Use and Acute Coronary Syndrome, is active but no longer recruiting, sponsored by Hennepin Healthcare Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 233 participants
- Enrollment target
- 1
- Study location
Study Summary
Summary of the Project : Quitting smoking following acute coronary syndrome (ACS) can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality. Thus, a single, integrated treatment for both smoking and depression could be highly effective in reducing post-acute coronary syndrome mortality. Behavioral Activation (BA) is a well established treatment for depression and has recently shown promise as a treatment for smoking cessation. The investigators systematically developed an intervention integrating gold standard smoking cessation counseling with existing BA based mood management techniques for post-ACS smokers; Behavioral Activation Treatment for Cardiac Smokers (BAT-CS). Objective: For this R01 the investigators will evaluate the efficacy of using a single, integrated treatment that targets both depressed mood and smoking (BAT-CS).
Primary Outcome
Self-report of no smoking, not even a puff, for 7 days; then Bio-chemically confirmed with saliva cotinine or by carbon monoxide in a breath sample
Conditions Studied
Interventions
- BEHAVIORAL BAT-CS
- BEHAVIORAL Smoking Cessation and Health & Wellness
Study Locations (1)
Minnesota
- Hennepin County Medical Center - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 233 participants |
| Start Date | 2018-01-29 |
| Est. Completion | 2026-05-30 |
| Phase | NA |
What the registry record for NCT03413423 still lists
NCT03413423 is an interventional study that assigns participants to a tested intervention. The registered 233 participants enrollment target is mid-sized for trials with a published cap, below the 376-participant average among 76 other Tobacco Use trials with a reported enrollment target (38% lower).
The record links to 2 conditions, with Tobacco Use appearing as the primary indexed condition, and to 2 interventions - of which BAT-CS is the first listed.
NCT03413423 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT03413423 about?
NCT03413423 is a clinical study titled "Post Acute Cardiac Event Smoking (PACES) Study". Summary of the Project : Quitting smoking following acute coronary syndrome (ACS) can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality. Thus, a single, integrated treatment for both ...
What is the current status of trial NCT03413423?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 233 participants. The study started on 2018-01-29. Estimated completion is 2026-05-30.
What conditions does trial NCT03413423 study?
This clinical trial studies the following conditions: Tobacco Use, Acute Coronary Syndrome.
What interventions are being tested in trial NCT03413423?
The interventions under investigation include: BAT-CS (BEHAVIORAL), Smoking Cessation and Health & Wellness (BEHAVIORAL).
Who is sponsoring clinical trial NCT03413423?
This trial is sponsored by Hennepin Healthcare Research Institute, which has 63 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03413423 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03413423's enrollment target sits among peer trials
233 23rd of 76 higher than 54 of 76 other Tobacco Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Nonendoscopic Screening for Barrett's Esophagus in Veterans Without Chronic Reflux
RECRUITING · NA
-
Opioids, Low Nicotine Cigarettes, and Chronic Pain
RECRUITING · NA
-
Reach Through Equitable Implementation in Utah
RECRUITING · NA
-
RTMS Targets Neural Circuits for Smoking Cessation
RECRUITING · NA
-
Cigar Legislation and Regulation in Tobacco for the Young (Project CLARITY)
RECRUITING · NA
-
Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT06993844 · 233 participants · Phase 1
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
- NCT07141706 · 233 participants · Phase 1
A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors
- NCT04942717 · 234 participants · NA
Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values
- NCT05208671 · 234 participants · NA
Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI