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NCT05918861 · ClinicalTrials.gov registry record · Phase 3
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
A Phase 3 study of Acute Coronary Syndrome, sponsored by DalCor Pharmaceuticals.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 2,000
- Enrollment target
- 20
- Study locations
NCT05918861: Recruiting Phase 3 study of Acute Coronary Syndrome, sponsored by DalCor Pharmaceuticals.
NCT05918861 is a Phase 3 study of Acute Coronary Syndrome that is actively recruiting participants, run by DalCor Pharmaceuticals. The registered enrollment target is 2,000 participants, below the 2,672-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target (25% lower). The trial reports 20 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05918861, a Phase 3 study of Acute Coronary Syndrome, is actively recruiting participants, sponsored by DalCor Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 2,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
This is a placebo-controlled, randomized, double-blind, parallel group, phase 3 multicenter study in subjects recently hospitalized for ACS and with the appropriate genetic profile. Subjects will provide informed consent before any study-specific procedures are performed. A separate informed consent will be allowed for an initial pre-screening genetic testing. Subjects meeting the AA genotype will then consent to the full study and confirmatory genetic testing as required. Subject enrollment may begin in the hospital and will continue following release from the hospital or may begin following release from hospital. Screening procedures may be performed at the time of the index ACS event or anytime thereafter, with the condition that randomization must occur within the mandated window (up to12 weeks after the index event). Subjects will be assessed based on their medical history. Those who are likely to qualify will undergo Genotype Assay testing to evaluate genetic determination for the presence of AA genotype.
Primary Outcome
Time to patients experiencing major cardiovascular events
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Dalcetrapib
Study Locations (20)
California
- Research Site - Garden Grove
- Research Site - Huntington Beach
- Research Site - La Jolla
- Research Site - Long Beach
- Research Site - Los Angeles
- Research Site - Newport Beach
- Research Site - Newport Beach
- Research Site - San Francisco
- Research Site - Santa Barbara
- Research Site - Stanford
- Research Site - Torrance
Alabama
- Research Site - Alexander City
- Research Site - Birmingham
- Research Site - Fairhope
- Research Site - Huntsville
- Research Site - Mobile
Arizona
- Research Site - Scottsdale
- Research Site - Tucson
Arkansas
- Research Site - Jonesboro
- Research Site - North Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2023-10-03 |
| Est. Completion | 2027-08 |
| Phase | Phase 3 |
What NCT05918861 shows while recruiting
NCT05918861 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, below the 2,672-participant average among 40 other Acute Coronary Syndrome trials with a reported enrollment target (25% lower).
The record links to 1 condition, with Acute Coronary Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05918861 names 20 study sites across 4 states, led by California, Alabama, Arizona.
Frequently Asked Questions
What is clinical trial NCT05918861 about?
NCT05918861 is a clinical study titled "Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS". This is a placebo-controlled, randomized, double-blind, parallel group, phase 3 multicenter study in subjects recently hospitalized for ACS and with the appropriate genetic profile. Subjects will provide informed consent before any study-specific procedures are performed. A separate informed consent...
What is the current status of trial NCT05918861?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 2,000 participants. The study started on 2023-10-03. Estimated completion is 2027-08.
What conditions does trial NCT05918861 study?
This clinical trial studies the following conditions: Acute Coronary Syndrome.
What interventions are being tested in trial NCT05918861?
The interventions under investigation include: Placebo (DRUG), Dalcetrapib (DRUG).
Who is sponsoring clinical trial NCT05918861?
This trial is sponsored by DalCor Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05918861 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Coronary Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05918861's enrollment target sits among peer trials
2,000 10th of 40 higher than 30 of 40 other Acute Coronary Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Coronary Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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