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NCT03670056 · ClinicalTrials.gov registry record · Phase 2

Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy

A Phase 2 study of Small-cell Lung Cancer, sponsored by Yale University.

Active
Registry status
Phase 2
Development phase
25
Enrollment target
1
Study location

NCT03670056 is a Phase 2 study of Small-cell Lung Cancer that is active but no longer recruiting, run by Yale University. The registered enrollment target is 25 participants, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03670056, a Phase 2 study of Small-cell Lung Cancer, is active but no longer recruiting, sponsored by Yale University.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

This is a pilot study of patients who previously received platinum chemotherapy with recurrent SCLC to evaluate the change in the ratio of intratumoral Teff/Treg cells and clinical benefit of treatment with nivolumab and ipilimumab.

Conditions Studied

Interventions

  • DRUG Combination immunotherapy with Ipilimumab and Nivolumab

Study Locations (1)

Connecticut

  • Yale University, Yale Cancer Center - New Haven

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2018-12-06
Est. Completion 2025-12
Phase Phase 2

Sponsor

Yale University

1,492 total trials

What the Registry Record Tells You About NCT03670056

The ClinicalTrials.gov registry entry for NCT03670056 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 232-participant average among 79 other Small-cell Lung Cancer trials with a reported enrollment target (89% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Small-cell Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Combination immunotherapy with Ipilimumab and Nivolumab is the first listed.

NCT03670056 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT03670056 about?

NCT03670056 is a clinical study titled "Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy". This is a pilot study of patients who previously received platinum chemotherapy with recurrent SCLC to evaluate the change in the ratio of intratumoral Teff/Treg cells and clinical benefit of treatment with nivolumab and ipilimumab.

What is the current status of trial NCT03670056?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2018-12-06. Estimated completion is 2025-12.

What conditions does trial NCT03670056 study?

This clinical trial studies the following conditions: Small-cell Lung Cancer.

What interventions are being tested in trial NCT03670056?

The interventions under investigation include: Combination immunotherapy with Ipilimumab and Nivolumab (DRUG).

Who is sponsoring clinical trial NCT03670056?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03670056 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.