Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 7 of 30

ACTIVE NOT RECRUITING NA

Lifestyle, Exercise, and Nutrition Study Early After Diagnosis

NCT03314688

ACTIVE NOT RECRUITING

Imaging mGluR5 and Synaptic Density in Psychiatric Disorders

NCT03898297

ACTIVE NOT RECRUITING Phase 1

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II

NCT02710097

ACTIVE NOT RECRUITING Phase 1

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III

NCT02710331

ACTIVE NOT RECRUITING Phase 1

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I

NCT02709954

ACTIVE NOT RECRUITING

Pathogenetic Basis of Aortopathy and Aortic Valve Disease

NCT03440697

ACTIVE NOT RECRUITING Phase 1

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition

NCT02404688

ACTIVE NOT RECRUITING Phase 1

Cannabinoids, Learning, and Memory

NCT02407808

ACTIVE NOT RECRUITING NA

Enhancing Behavior and Brain Response to Visual Targets Using a Computer Game

NCT02118649

ACTIVE NOT RECRUITING Early Phase 1

Probing the Cannabinoid System in Individuals With a Family History of Psychosis

NCT02102113

ACTIVE NOT RECRUITING

Pilot Study of Gut Commensals in Antiphospholipid Syndrome

NCT01787305

ACTIVE NOT RECRUITING

Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries

NCT02004561

NOT YET RECRUITING NA

Culturally Adapted Contingency Management

NCT07443332

NOT YET RECRUITING NA

A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease

NCT07553377

NOT YET RECRUITING NA

ED PLWD/Care Partner Text Messaging

NCT07423871

NOT YET RECRUITING NA

Substance Use in Assault-Injured Young Adults

NCT07070414

NOT YET RECRUITING NA

Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health

NCT05218980

NOT YET RECRUITING NA

Effect of HBOT on Femoral Head Avascular Necrosis (AVN)

NCT06931301

NOT YET RECRUITING Phase 2

Inulin Supplementation for Reducing Inflammation and Knee Pain in Older Adults With Osteoarthritis

NCT07189585

NOT YET RECRUITING NA

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

NCT07460622

NOT YET RECRUITING NA

Theoretically Informed Behavioral Intervention

NCT06580184

NOT YET RECRUITING Phase 2

Pilot Study: Effects of Nimodipine on Alcohol Drinking

NCT06900998

NOT YET RECRUITING Phase 2

Effects of Nimodipine on Alcohol Drinking

NCT07681869

NOT YET RECRUITING Phase 1

The Effects of Psilocybin on Social Connectedness

NCT07693153

NOT YET RECRUITING Early Phase 1

Psilocybin Microdosing on Cognition, Mood and Quality of Life

NCT07449351

NOT YET RECRUITING Phase 3

DEPART Study at Yale

NCT07661342

NOT YET RECRUITING NA

Personal Health Libraries for Formerly Incarcerated Individuals

NCT05441306

NOT YET RECRUITING NA

Pre-exposure Prophylaxis (PrEP) Adherence for Black MSM

NCT06661343

NOT YET RECRUITING NA

The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain

NCT06706778

NOT YET RECRUITING NA

Glucose, Understanding, Integrated Digital Health, and Engagement (GUIDE) Study

NCT07689877

NOT YET RECRUITING

Unified Network for Integrated Fluid Collection at Yale

NCT07689864

NOT YET RECRUITING NA

Leveraging Chatbot to Improve PrEP in the Southern United States

NCT05968755

NOT YET RECRUITING NA

Accuracy of the Accuro 3S

NCT07458087

NOT YET RECRUITING NA

The Impact of Needle Manipulation and Accuracy Between Hand Held Automatic and Traditional Ultrasound Device

NCT05909085

NOT YET RECRUITING NA

Clinical Trial of Peer Support in the ED (PCORI)

NCT06556069

NOT YET RECRUITING Phase 3

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

NCT07281027

NOT YET RECRUITING Early Phase 1

Psilocybin as a Treatment for Chronic Pain in Smokers

NCT07118332

NOT YET RECRUITING Phase 2

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

NCT06996652

NOT YET RECRUITING NA

Sex Differences in E-Cigarette Perception

NCT07398976

NOT YET RECRUITING NA

Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes

NCT07553585

NOT YET RECRUITING NA

A Clinical Trial of Telehealth Treatment for Opioid Use Disorders

NCT07362082

NOT YET RECRUITING Phase 2

The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease

NCT07610369

NOT YET RECRUITING

EMS-Initiated Buprenorphine

NCT07475728

NOT YET RECRUITING Phase 1

Membrane Potential Mapping with18F-TPP

NCT07506616

NOT YET RECRUITING NA

Pragmatic Trial of Messaging to Providers About Treatment of Chronic Kidney Disease

NCT07430930

NOT YET RECRUITING Phase 2

Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain

NCT07306364

NOT YET RECRUITING NA

Promoting Palliative Care for People With Heart Failure

NCT06933875

NOT YET RECRUITING NA

Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 2

NCT07602218

NOT YET RECRUITING Phase 2

Sac-TMT for Active TNBC Brain Metastases

NCT07458113

COMPLETED NA

Adaptive Decision Support for Addiction Treatment (ADAPT) Serial Randomized Testing for Usability, Round 1

NCT07549126

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Yale University pipeline card: 1,492 registered trials from official public datasets.Report a data error.