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NCT04599504 · ClinicalTrials.gov registry record · Phase 2
Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)
A Phase 2 study of Obesity & Overweight and Loss-of-control Eating, sponsored by Yale University.
- Active
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04599504: Active Phase 2 study of Obesity & Overweight and Loss-of-control Eating, sponsored by Yale University.
NCT04599504 is a Phase 2 study of Obesity & Overweight and Loss-of-control Eating that is active but no longer recruiting, run by Yale University. The registered enrollment target is 60 participants, below the 113-participant average among 28 other Obesity & Overweight trials with a reported enrollment target (47% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04599504, a Phase 2 study of Obesity & Overweight and Loss-of-control Eating, is active but no longer recruiting, sponsored by Yale University.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test the effectiveness of lisdexamfetamine medication as a treatment for loss-of-control eating and weight following bariatric surgery. This is a controlled test of whether, amongst non-responders to acute treatments, lisdexamfetamine medication results in superior outcomes compared with placebo.
Primary Outcome
Loss-of-control eating frequency is a continuous variable of loss-of-control eating episodes assessed using the Eating Disorder Examination interview; Loss-of-control eating frequency will be based on the past 28 days and defined as loss-of-control eating episodes per month.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Lisdexamfetamine Dimesylate (Medication)
Study Locations (1)
Connecticut
- Yale School of Medicine - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-01-02 |
| Est. Completion | 2027-05 |
| Phase | Phase 2 |
What the registry record for NCT04599504 still lists
NCT04599504 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 113-participant average among 28 other Obesity & Overweight trials with a reported enrollment target (47% lower).
The record links to 2 conditions, with Obesity & Overweight appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04599504 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT04599504 about?
NCT04599504 is a clinical study titled "Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)". This study will test the effectiveness of lisdexamfetamine medication as a treatment for loss-of-control eating and weight following bariatric surgery. This is a controlled test of whether, amongst non-responders to acute treatments, lisdexamfetamine medication results in superior outcomes compared ...
What is the current status of trial NCT04599504?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2022-01-02. Estimated completion is 2027-05.
What conditions does trial NCT04599504 study?
This clinical trial studies the following conditions: Obesity & Overweight, Loss-of-control Eating.
What interventions are being tested in trial NCT04599504?
The interventions under investigation include: Placebo (OTHER), Lisdexamfetamine Dimesylate (Medication) (DRUG).
Who is sponsoring clinical trial NCT04599504?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04599504 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity & Overweight
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04599504's enrollment target sits among peer trials
60 17th of 28 higher than 11 of 28 other Obesity & Overweight trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity & Overweight trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Pharmacological and Behavioral Treatment After Bariatric Surgery: Acute (Stage 1)
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-
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Weight Regain Treatment Post-Bariatric Surgery
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