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NCT05288361 · ClinicalTrials.gov registry record

The DISCOVER INOCA Prospective Multi-center Registry

A clinical trial of Endothelial Dysfunction and Coronary Microvascular Dysfunction, sponsored by Yale University.

Active
Registry status
500
Enrollment target
9
Study locations

NCT05288361 is a study of Endothelial Dysfunction and Coronary Microvascular Dysfunction that is active but no longer recruiting, run by Yale University. The registered enrollment target is 500 participants, above the 81-participant average among 45 other Endothelial Dysfunction trials with a reported enrollment target (517% higher). The trial reports 9 study locations across 6 states.

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The verdict

NCT05288361, a study of Endothelial Dysfunction and Coronary Microvascular Dysfunction, is active but no longer recruiting, sponsored by Yale University.

ACTIVE NOT RECRUITING
Registry status
500 participants
Enrollment target
9
Study locations

Study Summary

The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.

Conditions Studied

Endothelial Dysfunction Coronary Microvascular Dysfunction Microvascular Angina Ischemia and No Obstructive Coronary Artery Disease Coronary Vasospasm Chest Pain With Normal Coronary Angiography

Interventions

  • DIAGNOSTIC_TEST Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire

Study Locations (9)

New York

  • New York Presbyterian-Brooklyn Methodist Hospital - Brooklyn
  • NYU Langone Health - New York
  • Columbia University Irving Medical Center - New York

California

  • UCLA Health - Los Angeles
  • Stanford Hospital - Stanford

Connecticut

  • Yale New Haven Hospital - New Haven

Georgia

  • Northeast Georgia Medical Center - Gainesville

Ohio

  • The Christ Hospital - Cincinnati

Pennsylvania

  • Thomas Jefferson University Hospital - Philadelphia

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2022-09-14
Est. Completion 2032-12-31

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT05288361

The ClinicalTrials.gov registry entry for NCT05288361 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 81-participant average among 45 other Endothelial Dysfunction trials with a reported enrollment target (517% higher). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Endothelial Dysfunction appearing as the primary indexed condition, and to 1 intervention - of which Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire is the first listed.

NCT05288361 reports 9 study locations spanning 6 distinct geographic areas - top geographies include New York, California, Connecticut.

Frequently Asked Questions

What is clinical trial NCT05288361 about?

NCT05288361 is a clinical study titled "The DISCOVER INOCA Prospective Multi-center Registry". The overall objective of this multi-center registry is to identify specific phenotypes of INOCA with both an anatomic evaluation (coronary angiography and intravascular imaging) and physiologic assessment with the Abbott Coroventis Coroflow Cardiovascular System, and to determine long-term outcomes.

What is the current status of trial NCT05288361?

This trial is currently active not recruiting. The enrollment target is 500 participants. The study started on 2022-09-14. Estimated completion is 2032-12-31.

What conditions does trial NCT05288361 study?

This clinical trial studies the following conditions: Endothelial Dysfunction, Coronary Microvascular Dysfunction, Microvascular Angina, Ischemia and No Obstructive Coronary Artery Disease, Coronary Vasospasm.

What interventions are being tested in trial NCT05288361?

The interventions under investigation include: Coroventis Coroflow Cardiovascular System and PressureWire™ X Guidewire (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT05288361?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05288361 being conducted?

This trial has 9 study locations across California, Connecticut, Georgia, New York, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.