Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 18 of 30

COMPLETED NA

Treatment for Nicotine Addiction in Women

NCT02448654

COMPLETED Phase 4

Ketamine Infusion for Adolescent Depression and Anxiety

NCT02579928

TERMINATED NA

Melatonin Treatment for Night-Eating Syndrome

NCT02500017

COMPLETED NA

Enhancement of Therapeutic Learning in OCD Using tDCS

NCT03572543

COMPLETED NA

Modification and Evaluation of the Educational Mobile Games Heroes of Knowledge in Children

NCT02546245

COMPLETED NA

Effects of Brief Training on Craving Regulation

NCT02153749

COMPLETED Phase 2

Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing IN Gammopathy Patients

NCT02566265

COMPLETED Phase 4

A Smoking Cessation Intervention for Yale Dining Employees

NCT02562521

COMPLETED Phase 1

Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism

NCT02552147

COMPLETED Phase 1

Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart Failure

NCT02546583

COMPLETED Phase 2

Oxytocin and Affect Processing in Posttraumatic Stress Disorder

NCT02546570

COMPLETED Phase 3

Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility

NCT02432209

COMPLETED Phase 1

Minocycline's Effects on Alcohol Responses in Humans

NCT02187211

COMPLETED NA

Neurofeedback for Obsessive-Compulsive Disorder (OCD)

NCT02206945

COMPLETED NA

Randomized Controlled Trial of Social Network Targeting in Honduras

NCT02694679

COMPLETED NA

Gaze Modification Strategies for Toddlers With Autism Spectrum Disorder

NCT02488226

TERMINATED NA

Full-Endoscopic vs Open Discectomy for the Treatment of Symptomatic Lumbar Herniated Disc

NCT02441959

TERMINATED Phase 1

The Sustained Effects of Ketamine

NCT02708849

TERMINATED

A Multi-center, Prospective Evaluation of Infants and Children With Congenital Ichthyosis

NCT02655861

COMPLETED

Exercise in Genetic Cardiovascular Conditions

NCT02549664

COMPLETED Phase 1

Does Sweet Taste Potentiate Nicotine Cue Reactivity?

NCT02499757

TERMINATED

Pilot Study for Verifying Endotracheal Tube Repositioning Using Ultrasound

NCT02407158

TERMINATED NA

MOMS Hubs- CT Dept of Social Services Block Grant

NCT02459925

COMPLETED Phase 1

Evaluating the Combination of MK-3475 and Sterotactic Body Radiotherapy in Patients With Metastatic Melanoma or NSCLC

NCT02407171

COMPLETED Phase 1

The Effect of Cognitive Enhancement as a Precursor to Computer Based Training for Cognitive Behavioral Therapy (CBT4CBT)

NCT02174614

COMPLETED NA

Stage III Community-based Efficacy Trial for Mothering From the Inside Out

NCT02955199

COMPLETED

Active Surveillance in Prostate Cancer, Imaging to Detect Radiographic Progression as an Endpoint (ASPIRE)

NCT02425592

COMPLETED

Intergenerational Blood Pressure Study

NCT03013179

COMPLETED NA

A Psychosocial Program Impact Evaluation in Jordan

NCT03012451

COMPLETED NA

The Effects of Minocycline in Opioid-maintained Patients

NCT02359006

COMPLETED NA

PLUS PINK: HHRP+ Adaptation for Women With HIV Under Community Supervision

NCT03175094

COMPLETED Phase 3

Buprenorphine Treatment for Opioid Dependence

NCT02187198

COMPLETED Early Phase 1

Role of Glucagon In Glucose Control in Cystic Fibrosis Related Diabetes

NCT02398383

TERMINATED Phase 4

Corticosteroid Dosage for Crohn's Disease Flare

NCT02392286

COMPLETED Phase 1

Window Trial 5-aza in HNSCC, T-tare

NCT02178072

COMPLETED Phase 1

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone

NCT02576912

COMPLETED NA

Investigating the Role of the Polyol Pathway in the Central Nervous System

NCT02272556

COMPLETED Phase 1

Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Intravenous Ketamine

NCT02289248

COMPLETED Early Phase 1

Ketamine Infusion for Social Anxiety Disorder

NCT02083926

COMPLETED NA

The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adults

NCT02335021

COMPLETED NA

PRIME vs Usual Care for Clinical High Risk

NCT02960451

COMPLETED NA

Comparison of Nasal Steroids After FESS in CRSwNP

NCT02194062

COMPLETED NA

Text Messaging for Smoking Cessation in College Health Clinics

NCT02191033

COMPLETED Early Phase 1

Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed Loop

NCT02135068

TERMINATED Early Phase 1

Randomized Controlled Trial of Aspirin vs Placebo in the Treatment of Pre-psychosis

NCT02047539

TERMINATED

Methionine and PBR28-PET (Peripheral Benzodiazepine Receptors) in Brain Metastases Following Radiosurgery

NCT02433171

COMPLETED

A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population

NCT03699696

COMPLETED Phase 4

Study of Postoperative Chest Tube Management

NCT02282462

COMPLETED Phase 2

A Phase IIa Multi-Center Study of 18F-FDG PET, Safety, and Tolerability of AZD0530 in Mild Alzheimer's Disease

NCT02167256

COMPLETED NA

Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo

NCT02317744

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.