Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02272556 · ClinicalTrials.gov registry record · NA
Investigating the Role of the Polyol Pathway in the Central Nervous System
A NA study, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 138
- Enrollment target
NCT02272556: Completed NA study, sponsored by Yale University.
NCT02272556 is a NA study that has completed, run by Yale University. The registered enrollment target is 138 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02272556, a NA study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 138 participants
- Enrollment target
Study Summary
Patients will undergo magnetic resonance spectroscopy (MRS) scanning to noninvasively measure intracerebral and plasma metabolite levels at baseline and following 2 and 4 hours of hyperglycemia. Subjects will also undergo a lumbar puncture at a separate occasion to assess cerebrospinal fluid levels of metabolites.
Primary Outcome
metabolite levels will be measured by MRS
Interventions
- OTHER Brain MRS during hyperglycemic clamp
- OTHER Analysis of Metabolites in cerebrospinal fluid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2015-02 |
| Est. Completion | 2022-05-18 |
| Phase | NA |
What the finished NCT02272556 record still lists
NCT02272556 is an interventional study that assigns participants to a tested intervention. The registered 138 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Brain MRS during hyperglycemic clamp is the first listed.
NCT02272556 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02272556 about?
NCT02272556 is a clinical study titled "Investigating the Role of the Polyol Pathway in the Central Nervous System". Patients will undergo magnetic resonance spectroscopy (MRS) scanning to noninvasively measure intracerebral and plasma metabolite levels at baseline and following 2 and 4 hours of hyperglycemia. Subjects will also undergo a lumbar puncture at a separate occasion to assess cerebrospinal fluid levels ...
What is the current status of trial NCT02272556?
This trial is currently completed. It is a NA study. The enrollment target is 138 participants. The study started on 2015-02. Estimated completion is 2022-05-18.
What interventions are being tested in trial NCT02272556?
The interventions under investigation include: Brain MRS during hyperglycemic clamp (OTHER), Analysis of Metabolites in cerebrospinal fluid (OTHER).
Who is sponsoring clinical trial NCT02272556?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02272556's enrollment target sits among peer trials
138 720th of 2000 higher than 1,279 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04402788 · 138 participants · Phase 2
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
- NCT04883255 · 138 participants · Early Phase 1
Cannabis Use, Cognition, and the Endocannabinoid System in HIV
- NCT05620784 · 138 participants · Phase 3
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
- NCT05832086 · 138 participants · Phase 2
Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia