Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 19 of 30

COMPLETED

Active Surveillance of the Small Renal Mass

NCT02204800

TERMINATED NA

Effect of Use of Straw on Tolerability and Quality of Split Dose 4l-PEG Preparation

NCT02317731

TERMINATED Phase 2

Neoadj ph 2 AI Plus Everolimus in Postmenopausal Women w/ ER Pos/HER2 Neg, Low Risk Score

NCT02236572

COMPLETED Phase 1

The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism

NCT02262026

COMPLETED

Continuous Glucose Monitoring in Youth With Type 2 Diabetes

NCT02293577

COMPLETED NA

Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE)

NCT02310152

COMPLETED

The Human Microbiome in Immune-Mediated Diseases

NCT02394964

COMPLETED Phase 1

Role of Omalizumab in Reducing the Incidence of Oxaliplatin-induced Hypersensitivity Reaction

NCT02266355

COMPLETED Phase 1

GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration

NCT02302976

TERMINATED

Biological Biomarkers in MOMS Partnership

NCT02438514

TERMINATED NA

The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in Adolescents

NCT02499705

COMPLETED Phase 1

Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1

NCT02179034

COMPLETED NA

Novel Treatment to Enhance Smoking Cessation Before Cancer Surgery

NCT02402023

COMPLETED NA

Pilot for The Breast Cancer Endocrine Therapy Adherence (BETA) Trial

NCT02256670

COMPLETED Phase 1

Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing In Gammopathy Patients

NCT02267733

COMPLETED NA

Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults

NCT02498145

COMPLETED NA

Smartphone Application for Smoking Cessation

NCT02134509

COMPLETED NA

Automated Bilingual Computerized Alcohol Screening and Intervention in Latinos (AB-CASI)

NCT02247388

COMPLETED NA

The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis

NCT02282878

COMPLETED NA

The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity and Preference - Pilot

NCT02335008

COMPLETED Early Phase 1

Intranasal Oxytocin Administration and the Neural Correlates of Social and Non-Social Visual Perception

NCT02238379

COMPLETED NA

Loss of Control Eating Following Weight Loss Surgery

NCT02259322

COMPLETED NA

Reducing Operative and Post-operative Morbidity in Living Kidney Donors With the Airseal System

NCT02262039

COMPLETED NA

Neural Mechanisms of CBT for Anxiety in Autism (Open Pilot Study)

NCT02225808

COMPLETED

SHOCK US STUDY: Fluid Responsiveness in Sepsis Measured by Ultrasonography

NCT02170233

COMPLETED NA

LATCH: Lactation Advice Thru Texting Can Help

NCT02214849

TERMINATED

Restoring Glutathione Synthesis With Tecfidera: An in Vivo H-MRS Single-Arm Study at 7T in Patients With RR MS

NCT02218879

COMPLETED Phase 3

Optimal Treatment for Women With a Persisting Pregnancy of Unknown Location

NCT02152696

COMPLETED NA

A Reinforcement Approach to Improve Diabetes Management

NCT02167243

COMPLETED NA

Irritable Bowel Syndrome and Food Sensitivity

NCT02186743

COMPLETED NA

Using Video Modeled Social Stories to Improve Oral Hygiene in Children With Autism Spectrum Disorder

NCT02003820

COMPLETED Early Phase 1

Varenicline + Prazosin for Heavy Drinking Smokers

NCT02193256

COMPLETED Phase 1

Pilot Trial of KD018 With Neo-Adjuvant Concurrent Chemo-Radiation Therapy in Patients With Locally Advanced Rectal Cancer

NCT02178644

COMPLETED NA

Mindfulness Interventions and Chronic Widespread Pain in Adolescents

NCT02190474

COMPLETED NA

PET Imaging in Cocaine Self Administration

NCT02181491

COMPLETED Phase 2

Tofacitnib for the Treatment of Alopecia Areata and Variants

NCT02197455

COMPLETED NA

Improving Cancer Family Caregivers' Knowledge and Communication About Care Options

NCT02616107

TERMINATED NA

Cirrhosis Readmission Telehealth Project

NCT02313896

COMPLETED

HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)

NCT03583138

COMPLETED NA

Computerized Cognitive Behavioral Therapy and Electroconvulsive Therapy

NCT02176473

COMPLETED NA

Integrating Palliative Care Into Self-Management of Breast Cancer

NCT02148575

COMPLETED Phase 2

Does Guanfacine Attenuate Stress-Induced Drinking?

NCT02164422

TERMINATED NA

The Role of Obstructive Sleep Apnea in Children With Fatty Liver Disease

NCT02134522

TERMINATED Early Phase 1

N-acetylcysteine Effects on Tetrahydrocannabinol

NCT02335060

COMPLETED Phase 2

BeatMG: Phase II Trial of Rituximab In Myasthenia Gravis

NCT02110706

COMPLETED

Prostate Cancer Screening in Men With Germline BRCA2 Mutations

NCT02154672

COMPLETED Phase 1

Texting to Promote Tobacco Abstinence in Emergency Department Smokers: A Pilot Study

NCT02081144

COMPLETED Phase 2

Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic

NCT02094872

TERMINATED Phase 1

FAAH Inhibitor Trial for Adults With Tourette Syndrome

NCT02134080

TERMINATED NA

Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO PET

NCT02152670

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.