Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 17 of 30

COMPLETED NA

Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status

NCT02907931

COMPLETED Phase 2

Topical Tofacitinib for the Treatment of Alopecia Areata and Its Variants

NCT02812342

COMPLETED NA

A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk

NCT02929069

COMPLETED NA

Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation

NCT02907944

COMPLETED

A Study Comparing the Quality of Life of Patients in the Treatment of Eczema by Pediatric Generalists and Specialists

NCT02916888

COMPLETED

Prehospital Use of Ultrasound in Undifferentiated Shortness of Breath

NCT02638649

COMPLETED Phase 2

A Randomized Trial of a Combination of Nintedanib/Placebo in Combination With Induction Chemotherapy for Patients With Refractory or First Relapse Acute Myeloid Leukemia

NCT02665143

COMPLETED

Validation and Refinement of Noninvasive Diagnostic Biomarkers for Endometriosis, The ENDOmarker Protocol

NCT03161704

COMPLETED NA

Impact of Immediate Point-of-Care Ultrasound on Patients With Cardiopulmonary Symptoms in the Emergency Department

NCT02861508

COMPLETED NA

Bright 1 Bodies Weight Management Program

NCT02768987

COMPLETED Phase 2

Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3)

NCT02864147

COMPLETED NA

Shave Margins vs. Standard Partial Mastectomy in Breast Cancer Patients

NCT02772731

TERMINATED Phase 3

Prevention of Delirium in Inpatients Utilizing Melatonin

NCT02654314

COMPLETED Phase 2

Does CERC-501 Attenuate Stress-precipitated Smoking Lapse?

NCT02800928

COMPLETED

Development of Patient Centered Virtual Multimedia Interactive Informed Consent Tool to Improve Patient Comprehension and Consent

NCT02537886

COMPLETED Phase 2

Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer (NSCLC)

NCT02681549

COMPLETED Early Phase 1

Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence

NCT02994875

COMPLETED

SPECT/CT Imaging of Skeletal Muscle Perfusion

NCT02791204

COMPLETED Phase 1

Investigating the Central and Peripheral Mechanisms by Which Glucocorticoids Affect Hunger

NCT02722200

COMPLETED Phase 1

Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and Pregnenolone: Sub-Study I

NCT02811939

COMPLETED Phase 4

Progesterone Augmentation of Nicotine Replacement Therapy Study

NCT02685072

COMPLETED NA

Bridge Occlusion Balloon in Lead Extraction Procedure

NCT02714153

COMPLETED NA

CBT for Anxiety in Children With Autism

NCT02725619

COMPLETED

Study to Investigate Adipocyte Cell and Lipid Turnover in Obese Adolescents

NCT02395003

COMPLETED NA

Insomnia Self-Management in Heart Failure

NCT02660385

COMPLETED NA

A Mail and Video-based Weight Loss Trial in Breast Cancer Survivors

NCT02681965

COMPLETED Phase 2

Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects

NCT02487485

COMPLETED

A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid Dependence

NCT02718352

TERMINATED NA

A Pilot Trial of Curcumin Effects on Cognition in Schizophrenia

NCT02476708

TERMINATED Phase 2

Trial Comparing Early Laparoscopic Enterolysis Versus Nonoperative Management for High-grade SBO

NCT02692638

COMPLETED NA

Physical Activity and Glycemic Control in Adolescents

NCT02674828

COMPLETED NA

Investigation Into the Effects of Blood Glucose Levels Upon Eating Behavior in Lean and Obese Non-diabetic and Diabetic Subjects

NCT02673203

COMPLETED Phase 2

Cannabidiol Treatment in Patients With Early Psychosis

NCT02504151

COMPLETED NA

Indoor Air Pollution and Children With Asthma: An Intervention Trial

NCT02258893

COMPLETED NA

Personalized Intervention Program: Tobacco Treatment for Patients at Risk for Lung Cancer (PIP)

NCT02658032

COMPLETED NA

Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin Infusion

NCT02673138

COMPLETED NA

Tracking Intervention Effects With Eye Tracking

NCT02856061

COMPLETED Phase 1

Assessing the Role of a Fermented Soy Extract in Inflammation and the Human Microbiome

NCT02656056

COMPLETED

Sleep, Coping and Executive Functioning in Youth With Type 1 Diabetes

NCT02908555

COMPLETED Phase 2

Males, Antioxidants, and Infertility Trial

NCT02421887

COMPLETED NA

Novel and Scalable Internet Supplemented Weight Loss Treatment in Primary Care

NCT02578199

TERMINATED Phase 2

Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy

NCT02727998

COMPLETED

Perioperative Blood Pressures and Chronic Hypertension

NCT02136810

COMPLETED

Associations of Socioeconomic Adversity and Sleep With Allostatic Load Among Toddlers

NCT03419871

COMPLETED Phase 1

Pharmacokinetics of Doxorubicin in cTACE of Liver Cancer

NCT02753881

COMPLETED Phase 1

Investigating the Interactions of AZD0530 With Alcohol in Social Drinkers

NCT02732587

COMPLETED NA

Automated Recovery Line for Medication Assisted Treatment

NCT02124980

COMPLETED Phase 1

Neoadjuvant MEDI4736 Concomitant With Weekly Nab-paclitaxel and Dose-dense AC for Stage I-III Triple Negative Breast Cancer

NCT02489448

COMPLETED NA

Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse

NCT02616094

TERMINATED Phase 2

Single Agent Versus Combination Chemotherapy to Treat High-risk Elderly With Non-small Cell Lung Cancer

NCT02590003

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.