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NCT02708849 · ClinicalTrials.gov registry record · Phase 1
The Sustained Effects of Ketamine
A Phase 1 study, sponsored by Yale University.
- Terminated
- Registry status
- Phase 1
- Development phase
- 3
- Enrollment target
NCT02708849: Clinical Trial Phase 1 study, sponsored by Yale University.
NCT02708849 is a Phase 1 study that was terminated before completion, run by Yale University. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02708849, a Phase 1 study, was terminated before completion, sponsored by Yale University.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 3 participants
- Enrollment target
Study Summary
The purpose of the study is to characterize the effects of a single, sub-anesthetic dose of ketamine in rs-fMRI in healthy subjects. Post-ketamine rs-fMRI data will demonstrate a pattern of increased global brain connectivity (GBC) in fronto-temporal cortex.
Primary Outcome
24 hours post infusion fMRI data
Interventions
- DRUG Placebo
- DRUG Ketamine
- DRUG Lamotrigine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2015-06 |
| Est. Completion | 2020-03 |
| Phase | Phase 1 |
Why NCT02708849 stopped before completion
NCT02708849 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02708849 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02708849 about?
NCT02708849 is a clinical study titled "The Sustained Effects of Ketamine". The purpose of the study is to characterize the effects of a single, sub-anesthetic dose of ketamine in rs-fMRI in healthy subjects. Post-ketamine rs-fMRI data will demonstrate a pattern of increased global brain connectivity (GBC) in fronto-temporal cortex.
What is the current status of trial NCT02708849?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2015-06. Estimated completion is 2020-03.
What interventions are being tested in trial NCT02708849?
The interventions under investigation include: Placebo (DRUG), Ketamine (DRUG), Lamotrigine (DRUG).
Who is sponsoring clinical trial NCT02708849?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02708849's enrollment target sits among peer trials
3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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