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NCT02448654 · ClinicalTrials.gov registry record · NA
Treatment for Nicotine Addiction in Women
A NA study of Nicotine Dependence, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT02448654: Completed NA study of Nicotine Dependence, sponsored by Yale University.
NCT02448654 is a NA study of Nicotine Dependence that has completed, run by Yale University. The registered enrollment target is 36 participants, below the 186-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02448654, a NA study of Nicotine Dependence, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to use a medication tolcapone and or placebo to test if the symptoms of nicotine withdrawal lessens , and or changes in smoking urges, and mental reasoning in female smokers over a 72 hour period.
Primary Outcome
The MNWS was the 8 item version, using VAS scales for each item (1-100), and MNWS score calculated as an average of all items (range of possible scores for MWNS at each timepoint was 0-100, with higher MNWS scores at each timepoint indicating more withdrawal symptoms (worse outcome). Timepoints reflect 1.) the baseline (beginning of the trial, not yet receiving any pills, not yet being asked to abstain from smoking; calculated as average of scores from two visits: ad libitum baseline visit and p
Conditions Studied
Interventions
- DRUG Tolcapone
- DRUG Sugar Pill
Study Locations (1)
Connecticut
- Veterans Administration Hospital - West Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2015-10-23 |
| Est. Completion | 2019-06-30 |
| Phase | NA |
What the finished NCT02448654 record still lists
NCT02448654 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 186-participant average among 67 other Nicotine Dependence trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Nicotine Dependence appearing as the primary indexed condition, and to 2 interventions - of which Tolcapone is the first listed.
NCT02448654 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT02448654 about?
NCT02448654 is a clinical study titled "Treatment for Nicotine Addiction in Women". The purpose of this study is to use a medication tolcapone and or placebo to test if the symptoms of nicotine withdrawal lessens , and or changes in smoking urges, and mental reasoning in female smokers over a 72 hour period.
What is the current status of trial NCT02448654?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2015-10-23. Estimated completion is 2019-06-30.
What conditions does trial NCT02448654 study?
This clinical trial studies the following conditions: Nicotine Dependence.
What interventions are being tested in trial NCT02448654?
The interventions under investigation include: Tolcapone (DRUG), Sugar Pill (DRUG).
Who is sponsoring clinical trial NCT02448654?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02448654 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Nicotine Dependence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02448654's enrollment target sits among peer trials
36 52nd of 67 higher than 16 of 67 other Nicotine Dependence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Nicotine Dependence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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