Yale University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Yale University sits in the top decile of US sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count).

1,492 total trials 254 currently recruiting 1005 completed early-phase tilt top decile by trial count

Yale University: 1,492 sponsored US clinical trials, 254 recruiting.

Yale University sponsors 1,492 registered US clinical trials on ClinicalTrials.gov, 254 of them currently recruiting, and 1,005 completed. 99 of these trials are in Phase 3-4 (later-stage) and 579 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Opioid Use Disorder, with 19 trials.

Top-decile sponsor footprint

Yale University ranks in the top decile of sponsors by registered trial count (#13 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

1,005 of 1,138 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,492 total, page 14 of 30

COMPLETED NA

A Team-based Approach to Improve Knowledge and Judgment Performance in Electronic Fetal Monitoring

NCT04040257

COMPLETED NA

Multimodal Sleep Intervention Using Wearable Technology

NCT03658954

TERMINATED Phase 2

Translating Neuroprediction Into Precision Medicine Via Brain Priming

NCT03370510

TERMINATED NA

Cognitive-Behavioral and Physical Activity Interventions for Binge Eating and Overweight

NCT03777189

COMPLETED NA

Feasibility Pilot of Bright Light in the Intensive Care Unit

NCT03568045

COMPLETED Early Phase 1

Zero Sodium Peritoneal Dialysate Protocol Pilot Study

NCT03801226

COMPLETED Phase 1

Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial

NCT03367533

COMPLETED NA

White Noise to Improve Sleep in the Medical Intensive Care Unit (MICU): a Pilot and Feasibility Study

NCT03755011

COMPLETED NA

Feasibility of an Activity Regimen in Patients With Advanced Stage Lung Cancer

NCT03352245

TERMINATED Phase 3

Nutrition and Prostate Cancer

NCT03532308

TERMINATED NA

Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

NCT03684187

COMPLETED Phase 1

Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.

NCT03356483

COMPLETED

Validating Imaging Biomarkers of Small Vessel Disease in Diabetic Individuals Using Advanced MRI Techniques.

NCT03754608

COMPLETED Early Phase 1

Mechanisms for Restoration of Hypoglycemia Awareness

NCT03738852

COMPLETED NA

Investigating the Effect of Onyx Sorghum on Blood Glucose in Individuals With Type 2 Diabetes

NCT03714451

COMPLETED NA

An Accessible Digital Intervention to Promote HIV Testing/Counseling and Prevention Among Adolescents

NCT03713034

COMPLETED Early Phase 1

Influence of Medication on Functional Connectivity

NCT03612713

COMPLETED Early Phase 1

Assessment of Cognitive Function Before and After Conversion From Immediate Release Tacrolimus to Envarsus XR.

NCT03410654

COMPLETED

Comparing an Inexpensive Handheld Ultrasound Machine and a Large Mobile Ultrasound System

NCT03764111

COMPLETED NA

OPTIONS: A Patient-Centered HIV Prevention Decision Aid for PrEP Uptake for Women With Substance Use in Treatment Settings

NCT03651453

COMPLETED NA

Yale-Harvard Hotel-based Closed-Loop Studies in Children (HY-GRAID)

NCT04255381

COMPLETED

Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization

NCT03438682

COMPLETED Phase 1

The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders

NCT03872128

COMPLETED NA

Digital Parent Training for Disruptive Behaviors in Children

NCT03697837

COMPLETED NA

Adapting an Evidence-based Intervention for Stigma-related Stress, Mental Health, and HIV Risk for MSM of Color in Small Urban Areas

NCT03464422

COMPLETED NA

Improving Pediatric Obesity Practice Using Prompts

NCT03648242

COMPLETED NA

Fatherhood Focused Family Violence Education Program

NCT03883932

COMPLETED NA

Perioperative Blood Pressure Screening to Improve Long-term Cardiovascular Health

NCT03634813

COMPLETED NA

Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders

NCT03585010

TERMINATED NA

The PrISICE Clinical Trial (Pre-Implantation Screening and Investigation on the Cryopreservation of Embryos)

NCT03371745

COMPLETED NA

Mechanisms of Obesity and Its Metabolic Complications in Youth

NCT03454828

COMPLETED NA

Effect of Mental Imagery Training on Brain Plasticity and Motor Function in Individuals With Parkinson's Disease

NCT03623386

COMPLETED NA

Bariatric Scalable Internet Treatments

NCT03680703

COMPLETED NA

Project EQuIP: Empowering Queer Identities in Psychotherapy

NCT03721276

COMPLETED NA

Cannabis Use and Relapse After One Week of Contingency Management Therapy

NCT04202146

COMPLETED Early Phase 1

Mechanism and Effects of Manipulating Chloride Homeostasis in Acute Heart Failure

NCT03446651

COMPLETED

Detection of Postoperative Respiratory Depression in High Risk Patients Utilizing Minute Ventilation Monitoring

NCT04017702

COMPLETED

Establishing Muscle Impedance Parameters With Electrical Impedance Myography

NCT03633318

COMPLETED Phase 1

APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma

NCT03502330

TERMINATED Early Phase 1

Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.

NCT03500484

COMPLETED NA

Peer-led Social Media Intervention to Prevent HIV Among Young Men Who Have Sex With Men (YMSM)

NCT04417946

COMPLETED NA

Global Response Assessment by Advanced Imaging and Myeloma Lesion Biopsies During Induction Therapy of Multiple Myeloma With Carfilzomib Lenalidomide Dexamethasone

NCT03375567

COMPLETED Early Phase 1

Metabotropic Glutamate Receptor-5 (mGlur5) Effects on Reward-Related fMRI-BOLD Activation in FHP and FHN

NCT03341715

TERMINATED NA

Neurofeedback of Amygdala Activity for Post-traumatic Stress Disorder

NCT03574974

COMPLETED NA

The Effect of Bolus Speed of Rapid-Acting Insulin Analog Absorption and Action in Individuals With Type 1 Diabetes

NCT03542682

TERMINATED Phase 2

An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis

NCT03359174

COMPLETED NA

Feasibility of Providing Computerized CBT in the Black Church

NCT03579290

COMPLETED Early Phase 1

Galantamine and CBT4CBT Pilot to Prevent Relapse.

NCT03547622

COMPLETED NA

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320

COMPLETED Early Phase 1

Effects of Flavors on Nicotine Reinforcement in Smokers

NCT03243630

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Phase Distribution

PhaseTrial count
Phase 1 312
Phase 2 267
Phase 3 52
Phase 4 47

What is open in the Yale University pipeline

254 recruiting of 1,492 indexed (17% open); 1,005 completed (67%).

Phase mix: 99 late (III/IV) vs 579 early (I/II) (early-phase heavy).

Top condition: Opioid Use Disorder (19 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Yale University: open-pipeline peers nationwide

Peers matched on 1,492 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Yale UniversityWashington University School of MedicineJohns Hopkins UniversityUniversity of PennsylvaniaNovartis PharmaceuticalsNYU Langone HealthCSL BehringPenn State UniversityUniversity of Hawaii
Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Yale University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,492 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Yale University page

1,492 registered trials is a research-attention snapshot, not an endorsement of Yale University or any single study.

  • 254 of Yale University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Opioid Use Disorder is the condition Yale University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Opioid Use Disorder trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Yale University pipeline card: 1,492 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.