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NCT03738852 · ClinicalTrials.gov registry record · Early Phase 1
Mechanisms for Restoration of Hypoglycemia Awareness
A Early Phase 1 study, sponsored by Yale University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 55
- Enrollment target
NCT03738852 is a Early Phase 1 study that has completed, run by Yale University. The registered enrollment target is 55 participants.
The verdict
NCT03738852, a Early Phase 1 study, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 55 participants
- Enrollment target
Study Summary
To assess if using the hypoglycemic clamp and functional magnetic resonance imaging (fMRI) scanning in hypoglycemia unaware and aware T1DM patients and healthy controls have showed distinct differences in patterns of brain responses. In particular, T1DM patients who are aware of hypoglycemia (T1DM-Aware) have greater activity in sensory integration brain regions (e.g. parietal lobe and caudate nucleus) in response to hypoglycemia, whereas hypoglycemia unaware T1DM patients (T1DM-Unaware) show no detectable changes in brain reward regions during hypoglycemia.
Interventions
- DRUG Insulin
- DEVICE Continuous Glucose Monitor (CGM)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2018-11-07 |
| Est. Completion | 2023-08-14 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03738852
The ClinicalTrials.gov registry entry for NCT03738852 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Insulin is the first listed.
NCT03738852 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03738852 about?
NCT03738852 is a clinical study titled "Mechanisms for Restoration of Hypoglycemia Awareness". To assess if using the hypoglycemic clamp and functional magnetic resonance imaging (fMRI) scanning in hypoglycemia unaware and aware T1DM patients and healthy controls have showed distinct differences in patterns of brain responses. In particular, T1DM patients who are aware of hypoglycemia (T1DM-A...
What is the current status of trial NCT03738852?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 55 participants. The study started on 2018-11-07. Estimated completion is 2023-08-14.
What interventions are being tested in trial NCT03738852?
The interventions under investigation include: Insulin (DRUG), Continuous Glucose Monitor (CGM) (DEVICE).
Who is sponsoring clinical trial NCT03738852?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
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