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NCT03454828 · ClinicalTrials.gov registry record · NA
Mechanisms of Obesity and Its Metabolic Complications in Youth
A NA study of Obesity, Childhood, sponsored by Yale University.
- Completed
- Registry status
- NA
- Development phase
- 38
- Enrollment target
- 1
- Study location
NCT03454828: Completed NA study of Obesity, Childhood, sponsored by Yale University.
NCT03454828 is a NA study of Obesity, Childhood that has completed, run by Yale University. The registered enrollment target is 38 participants, below the 343-participant average among 53 other Obesity, Childhood trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03454828, a NA study of Obesity, Childhood, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
The overarching goal of this project is to determine whether the effect of gut microbiota on human metabolism might be mediated by short chain fatty acids (SCFA) and whether the SCFA might modulate lipid metabolism.
Primary Outcome
Starting at 08:00, we began a 10-h, primed, continuous, peripheral venous infusion of 99% sodium \[d3\]-acetate with a priming dose of 200 μg · kg-1 · min-1 for 4 min and a continuous infusion rate of 59.5 μg · kg-1 · min-1 for 10 h. After 180 min from the start of the infusion, subjects received 20 g of lactulose per os, dissolved in 30 mL of water.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT obese carbohydrate diet
- DIETARY_SUPPLEMENT lean carbohydrate diet
Study Locations (1)
Connecticut
- Hospital Research Unit - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2018-08-18 |
| Est. Completion | 2024-06-30 |
| Phase | NA |
What the finished NCT03454828 record still lists
NCT03454828 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 343-participant average among 53 other Obesity, Childhood trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Obesity, Childhood appearing as the primary indexed condition, and to 2 interventions - of which obese carbohydrate diet is the first listed.
NCT03454828 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT03454828 about?
NCT03454828 is a clinical study titled "Mechanisms of Obesity and Its Metabolic Complications in Youth". The overarching goal of this project is to determine whether the effect of gut microbiota on human metabolism might be mediated by short chain fatty acids (SCFA) and whether the SCFA might modulate lipid metabolism.
What is the current status of trial NCT03454828?
This trial is currently completed. It is a NA study. The enrollment target is 38 participants. The study started on 2018-08-18. Estimated completion is 2024-06-30.
What conditions does trial NCT03454828 study?
This clinical trial studies the following conditions: Obesity, Childhood.
What interventions are being tested in trial NCT03454828?
The interventions under investigation include: obese carbohydrate diet (DIETARY_SUPPLEMENT), lean carbohydrate diet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03454828?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03454828 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03454828's enrollment target sits among peer trials
38 48th of 53 higher than 6 of 53 other Obesity, Childhood trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity, Childhood trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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