VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 18 of 34

COMPLETED NA

Enhancement of PTSD Treatment With Computerized Executive Function Training

NCT03260127

COMPLETED Phase 2

Testosterone and Long Pulse Stimulation After SCI

NCT03345576

COMPLETED Phase 2

Systemic and Tumor-Directed Therapy for Oligometastatic Prostate Cancer

NCT03298087

COMPLETED NA

Incline Training to Personalize Motor Control Interventions After Stroke

NCT03561246

TERMINATED Phase 4

Metabolic Effects of Natriuretic Peptide Hormones

NCT03397966

TERMINATED

Arm Exercise Versus Pharmacologic Stress Testing for Clinical Outcome

NCT03449888

TERMINATED Phase 4

Regulation of Insulin Secretion by the GLP-1 Receptor

NCT02844907

COMPLETED NA

Non-Pharmacological Treatments for Insomnia in Chronic Traumatic Brain Injury

NCT03261674

COMPLETED NA

Treating Sleep Apnea in Women Veterans

NCT03377452

COMPLETED NA

Improving Housing Outcomes for Homeless Veterans

NCT03646149

COMPLETED NA

Cognitive Training for PTSD

NCT03316196

COMPLETED NA

Prospective RCT Of Water Exchange (WE) vs. WE Plus Cap-Assisted Colonoscopy

NCT03160859

COMPLETED NA

Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care

NCT03539068

COMPLETED NA

Peer Support for Exercise in Older Veterans With Psychotic Disorders

NCT02958007

COMPLETED Early Phase 1

Exercise and NO in HFrEF

NCT03136029

COMPLETED NA

Optimizing Treatment Response in VA Specialized Intensive/Inpatient PTSD Programs

NCT03533608

COMPLETED NA

Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia

NCT03482310

TERMINATED Phase 2

Robotic Training for Stroke Neurorehabilitation

NCT02639390

COMPLETED NA

A Technology Assisted Care Transition Intervention for Veterans With CHF or COPD

NCT02632552

COMPLETED Phase 2

Low Dose Naltrexone for Chronic Pain From Arthritis

NCT03008590

COMPLETED NA

Peer-Delivered Whole Health Coaching for Veterans With PTSD

NCT03364192

COMPLETED NA

Optimizing Function and Independence Through iHI-FIVES

NCT03474380

COMPLETED NA

Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation

NCT03532100

TERMINATED Phase 2

Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C

NCT02971033

COMPLETED NA

Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

NCT03191266

COMPLETED NA

Acupuncture for PTSD

NCT02869646

COMPLETED NA

Modulation of the Intestinal Microbiome by a High Protein Diet

NCT04812964

COMPLETED NA

tDCS Plus Virtual Reality for PTSD

NCT03372460

COMPLETED

Precision Assessment of Platelet Rich Plasma for Joint Preservation

NCT03460236

COMPLETED Phase 4

Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

NCT03265964

COMPLETED

Medications for Opioid Use Disorders (MOUD) Via Telemedicine

NCT03566459

TERMINATED NA

Spatial Cognitive Training

NCT03423654

COMPLETED NA

Hearing Aids and the Brain

NCT03279510

COMPLETED NA

Financial vs. Non-Financial Rewards for Weight Loss and Weight Maintenance

NCT02957539

COMPLETED Phase 3

Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson Disease

NCT03149809

COMPLETED NA

CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes

NCT02535923

COMPLETED NA

Self-management of Blood Pressure Medication for Hypertensive Veterans

NCT03224624

COMPLETED NA

DVD Lifestyle Intervention

NCT03260140

COMPLETED

Neurobiology of Alcohol and Nicotine Co-Addiction

NCT03338933

COMPLETED NA

Transfusion Trigger After Operations in High Cardiac Risk Patients

NCT03229941

COMPLETED NA

Genetic Influences on Response to Gait Rehabilitation in Parkinson's Disease

NCT03607695

COMPLETED NA

INcreasing Veteran EngagemeNT to Prevent Diabetes (INVENT)

NCT03403231

COMPLETED Phase 2

Stimulant Oxytocin Study

NCT03016598

COMPLETED Phase 4

Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics

NCT03012529

COMPLETED NA

Improving Veteran Adherence to Treatment for PTSD Through Partnering With Families

NCT03256227

COMPLETED NA

The Peer Assisted Lifestyle Intervention

NCT03163264

COMPLETED NA

Weight Loss Treatment for Veterans With Binge Eating

NCT03234881

COMPLETED NA

Cervical Electrical Stimulation for ALS

NCT03411863

COMPLETED NA

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

NCT03056157

COMPLETED NA

Development of a Weight Maintenance Intervention for Bariatric Surgery Patients

NCT03246672

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.