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NCT03449888 · ClinicalTrials.gov registry record
Arm Exercise Versus Pharmacologic Stress Testing for Clinical Outcome
A clinical trial, sponsored by VA Office of Research and Development.
- Terminated
- Registry status
- 133
- Enrollment target
NCT03449888: Clinical Trial study, sponsored by VA Office of Research and Development.
NCT03449888 is a clinical trial that was terminated before completion, run by VA Office of Research and Development. The registered enrollment target is 133 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03449888 was terminated before completion, sponsored by VA Office of Research and Development.
- TERMINATED
- Registry status
- 133 participants
- Enrollment target
Study Summary
This is a 5-year clinical trial to evaluate whether arm exercise electrocardiographic (ECG) stress testing without or with coronary artery calcium scoring (-/+ CAC) is non-inferior to treadmill ECG stress testing -/+ CAC and pharmacologic myocardial perfusion imaging as an initial evaluation to detect obstructive coronary artery disease, determined by cardiac computed tomographic angiography (CTA) and to predict clinical outcome, defined by a primary clinical endpoint of the composite of cardiovascular (CV) mortality, myocardial infarction, and 90-day post-stress test coronary artery revascularization and secondary clinical endpoints of all-cause mortality and CV mortality.
Primary Outcome
Death from a cardiovascular cause, occurrence of myocardial infarction, and 90-day post-stress test coronary artery revascularization by any technique determined from VA, National Death Index, Missouri Health and Human Services, and non-VA medical records, and patient follow-up information.
Interventions
- PROCEDURE Regadenoson myocardial perfusion imaging stress test
- PROCEDURE Arm exercise electrocardiographic stress test
- PROCEDURE Treadmill electrocardiographic stress test
- PROCEDURE Coronary artery calcium score and cardiac computed tomographic angiography
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 133 participants |
| Start Date | 2018-07-01 |
| Est. Completion | 2021-02-05 |
Why NCT03449888 stopped before completion
NCT03449888 is an observational study that tracks outcomes without assigning an intervention. The registered 133 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 4 interventions - of which Regadenoson myocardial perfusion imaging stress test is the first listed.
NCT03449888 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03449888 about?
NCT03449888 is a clinical study titled "Arm Exercise Versus Pharmacologic Stress Testing for Clinical Outcome". This is a 5-year clinical trial to evaluate whether arm exercise electrocardiographic (ECG) stress testing without or with coronary artery calcium scoring (-/+ CAC) is non-inferior to treadmill ECG stress testing -/+ CAC and pharmacologic myocardial perfusion imaging as an initial evaluation to dete...
What is the current status of trial NCT03449888?
This trial is currently terminated. The enrollment target is 133 participants. The study started on 2018-07-01. Estimated completion is 2021-02-05.
What interventions are being tested in trial NCT03449888?
The interventions under investigation include: Regadenoson myocardial perfusion imaging stress test (PROCEDURE), Arm exercise electrocardiographic stress test (PROCEDURE), Treadmill electrocardiographic stress test (PROCEDURE), Coronary artery calcium score and cardiac computed tomographic angiography (PROCEDURE).
Who is sponsoring clinical trial NCT03449888?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
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