VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 17 of 34

COMPLETED Phase 1

Vagal Nerve Stimulation to Probe Inflammation and Brain in Post-traumatic Stress

NCT03858985

COMPLETED Phase 1

rTMS for Emotional Difficulties in Verterans

NCT03749967

COMPLETED NA

Incorporating Veterans' Preferences Into Lung Cancer Screening Decisions

NCT02899754

COMPLETED NA

Aging Back Clinics

NCT03564600

COMPLETED NA

Dietary Prevention of Heart Failure in Hypertensive Metabolic Syndrome

NCT03170375

COMPLETED Phase 2

Preventing Diabetic Foot Ulcers Through Cleaner Feet

NCT03503370

COMPLETED NA

Stimulation for Colonic Motility

NCT02641483

COMPLETED NA

Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI

NCT03664765

COMPLETED NA

Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients

NCT03524729

COMPLETED NA

Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD

NCT03449576

COMPLETED NA

Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI

NCT04044456

COMPLETED NA

Practical Telemedicine to Improve Control and Engagement for Veterans With Clinic-Refractory Diabetes Mellitus

NCT03520413

COMPLETED Phase 1

Spinal Excitation to Enhance Mobility

NCT03667573

COMPLETED Phase 2

Management of Cardiovascular Disease in Kidney Disease (MaCK) Study

NCT03636152

COMPLETED Phase 4

Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

NCT03298945

COMPLETED NA

Discontinuation of Hypnotics in Older Veterans

NCT03511209

COMPLETED NA

Anxiety in Older Veterans

NCT02400723

TERMINATED NA

Enhancing Functional Capacity in Older Adults With Short Session High Intensity Interval Training

NCT03750006

COMPLETED

Computerized Vestibular Rehabilitation

NCT03589859

COMPLETED NA

The Secure Messaging for Medication Reconciliation Tool (SMMRT) Trial

NCT02482025

COMPLETED NA

Selecting Effective Combinations of Treatment for Low Back Pain

NCT03520387

TERMINATED Phase 2

Microbiota or Placebo After Antimicrobial Therapy for Recurrent C. Difficile at Home (MATCH)

NCT03005379

COMPLETED NA

Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling

NCT03177265

COMPLETED NA

A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD

NCT03225859

COMPLETED NA

Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment

NCT03590327

TERMINATED NA

Machine Learning Neurofeedback for PTSD

NCT03482466

TERMINATED Early Phase 1

Pneumococcal Conjugate Vaccine in Aging Renal Transplant

NCT03802994

COMPLETED NA

Recovering From Intimate Partner Violence Through Strengths and Empowerment (RISE)

NCT03261700

COMPLETED NA

Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT

NCT03653637

COMPLETED NA

Self-Management of Continuous Positive Airway Pressure Settings

NCT03536572

COMPLETED NA

Increasing Physical Activity in COPD Through Rhythmically Enhanced Music

NCT03655028

COMPLETED NA

Communication and Activation in Pain to Enhance Relationships and Treat Pain With Equity

NCT03562793

COMPLETED NA

Measuring and Improving the Safety of Test Result Follow-Up

NCT04166240

COMPLETED

Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life

NCT03615222

COMPLETED NA

Brief Cognitive Behavioral Therapy for Chronic Pain

NCT03490981

COMPLETED NA

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

NCT03377270

TERMINATED Phase 2

Optimal Treatment of Veterans With PTSD and Comorbid OUD

NCT03605342

COMPLETED NA

Pilot Study of Peer-Supported Online Problem-Solving Program

NCT03555435

COMPLETED NA

Heart Health Buddies: Peer Support to Decrease CVD Risk

NCT03646656

COMPLETED NA

Transcranial Direct Current Stimulation for Post-stroke Gait Rehab

NCT03666533

COMPLETED NA

Connecting Women to Care: Home-based Psychotherapy for Women With MST Living in Rural Areas

NCT03429166

COMPLETED NA

Improving Outcomes Among Medical/Surgical Inpatients With Alcohol Use Disorders

NCT03258632

COMPLETED Phase 1

Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia

NCT03034356

COMPLETED Phase 2

Lipoic Acid for Progressive Multiple Sclerosis (MS)

NCT03161028

COMPLETED NA

Evaluating the Use of Peer Specialists to Deliver Cognitive Behavioral Social Skills Training

NCT03467243

COMPLETED Phase 2

Transdiagnostic Cognitive Behavioral Treatment for Anxiety

NCT03810456

COMPLETED NA

The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans

NCT03521999

COMPLETED Phase 3

Beta Adrenergic Antagonist for the Healing of Chronic DFU

NCT03282981

COMPLETED NA

Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness

NCT03208036

COMPLETED NA

Cognitive Rehabilitation Therapy for Mild Cognitive Impairment

NCT03225482

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.