VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 19 of 34

COMPLETED NA

Spanish Intervention for Caregivers of Veterans With Stroke

NCT03142841

COMPLETED NA

Evaluation of a Spasticity Management Program for People With Multiple Sclerosis

NCT03166930

COMPLETED NA

Neurohormonal Benefits of Exercise in Fibromyalgia and PTSD

NCT03236467

COMPLETED NA

Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation

NCT03314584

COMPLETED NA

Effects of rTMS on Brain Activation in Aphasia

NCT03292471

COMPLETED NA

Pain and Smoking Study

NCT02971137

COMPLETED NA

Mindfulness for Anger in Veterans With PTSD

NCT02882802

COMPLETED NA

Improving Linkage to Health and Other Services for Veterans Leaving Incarceration

NCT02964897

COMPLETED NA

Pilot Testing a Home-Based Rehabilitation Intervention Designed to Improve Outcomes of Frail Veterans Following Cardiothoracic Surgery

NCT03299101

COMPLETED NA

Optimizing Physical Activity Outcomes After Total Knee Arthroplasty

NCT03226106

COMPLETED NA

Improving Psychosocial Functioning in Older Veterans With PTSD

NCT02803125

TERMINATED Phase 4

Frequent, Low-Dose Erythropoietin A Mechanistic Approach to Mitigate Adverse Cardiovascular Effects of Erythropoietin

NCT03277183

COMPLETED Phase 2

Topiramate and Prolonged Exposure

NCT03176953

COMPLETED NA

Remote Diagnosis and Management of Obstructive Sleep Apnea

NCT03007745

COMPLETED NA

Optimizing Function and Independence Through STRIDE

NCT03300336

COMPLETED Phase 1

Biofeedback to Increase Propulsion During Walking After Stroke

NCT02667392

COMPLETED NA

Virtual Reality for Phantom Limb Pain

NCT02784548

COMPLETED NA

Brain Markers of Improvements in Cognitive Functioning

NCT03490110

COMPLETED NA

Stay Strong: A Physical Activity Program for Afghanistan and Iraq Veterans

NCT02360293

COMPLETED

REACH VET Implementation Program Evaluation

NCT03280225

TERMINATED NA

Family Telemental Health Intervention for Veterans With Dementia

NCT03116464

COMPLETED NA

An Adjunctive Family Intervention for Individual Posttraumatic Stress Disorder Treatment

NCT02956434

COMPLETED NA

Improving Mind/Body Health and Functioning With Integrative Exercise

NCT02856412

COMPLETED NA

Improving Motor Function After Spinal Cord Injury

NCT01915095

COMPLETED NA

A Novel Strategy to Decrease Fall Incidence Post-Stroke

NCT02688777

COMPLETED NA

Improve Glaucoma Medication Adherence

NCT03052257

COMPLETED NA

Groups for Regaining Our Wellbeing

NCT03058952

COMPLETED NA

Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation

NCT03037983

COMPLETED NA

Predictors of Response to Insomnia Treatments for Gulf War Veterans

NCT03208049

COMPLETED NA

Impact of Family History and Decision Support on High-risk Cancer Screening

NCT02247336

TERMINATED Phase 4

Topiramate Treatment of Alcohol Use Disorders in African Americans

NCT03018704

COMPLETED NA

Development of a Patient Centered Mental Health Intervention for Recent Veterans

NCT02943408

COMPLETED

Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics

NCT02713217

COMPLETED Phase 3

Coenzyme Q10 Phase III Trial in Gulf War Illness

NCT02865460

COMPLETED NA

Patient-Centered Pain Care Using Artificial Intelligence and Mobile Health Tools

NCT02464449

COMPLETED NA

SAFER: A Brief Intervention Involving Family Members in Suicide Safety Planning

NCT03034863

COMPLETED NA

Collaborative Care for Women Veterans

NCT02950961

COMPLETED NA

Nutritional Perihabilitation in Older Veterans Undergoing Surgery

NCT03073811

COMPLETED Phase 2

Contralaterally Controlled Functional Electrical Stimulation Plus Video Games for Hand Therapy After Stroke

NCT03058796

COMPLETED NA

PRIME Care (PRecision Medicine In MEntal Health Care)

NCT03170362

COMPLETED NA

Telephone Coaching of Family Members of Veterans With Substance Abuse Problems

NCT03246646

COMPLETED Phase 2

Brain Amyloid and Vascular Effects of Eicosapentaenoic Acid

NCT02719327

COMPLETED NA

Novel Interventions for GWVI

NCT02661997

COMPLETED NA

Feasibility Study: fMRI Evaluation of Auricular PENFS for Fibromyalgia

NCT03008837

COMPLETED NA

Video-Enhanced Care Management for Medically Complex Veterans

NCT02962687

COMPLETED NA

SToRytelling to Improve DiseasE Outcomes in GOut: The STRIDE-GO2 Study

NCT02741700

COMPLETED NA

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

NCT03151083

COMPLETED NA

Veteran Peer Coaches Optimizing and Advancing Cardiac Health

NCT02697422

COMPLETED

Evaluation of Veteran-Directed Home and Community Based Services

NCT03145818

COMPLETED NA

Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit

NCT03648762

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.