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NCT03225482 · ClinicalTrials.gov registry record · NA

Cognitive Rehabilitation Therapy for Mild Cognitive Impairment

A NA study, sponsored by VA Office of Research and Development.

Completed
Registry status
NA
Development phase
193
Enrollment target

NCT03225482: Completed NA study, sponsored by VA Office of Research and Development.

NCT03225482 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 193 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT03225482, a NA study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
NA
Development phase
193 participants
Enrollment target

Study Summary

The number of older Veterans with Mild Cognitive Impairment (MCI) seeking care within the Veterans Affairs (VA) health care system is increasing and is expected to increase more rapidly as Vietnam era Veterans age. The cognitive effects of MCI and subsequent neurodegenerative disorders can adversely affect a Veteran's ability to function independently and failure to provide appropriate intervention can result in an increased need for healthcare services and VA benefits in the future. The VA currently spends over $19,000 annually per patient to care for Veterans with dementia (Zhu et al., 2009), and delaying the onset of dementia even by one to two years will result in substantial financial savings to the VA and quality of life gains for the Veteran. Since present pharmacological interventions have demonstrated limited efficacy, alternative treatments are needed. Therefore, an evidence-based cognitive training intervention that optimally addresses the needs of older Veterans with MCI is of critical importance to the VA patient care mission.

Primary Outcome

Change in composite z score on the following tests: Hopkins Verbal Learning Test-Revised (HVLT-R) Brief Visuospatial Memory Test-Revised (BVMT-R) Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) Digit Span WAIS-IV Coding Delis-Kaplan Executive Function System (D-KEFS) Trails, Number and Letter Sequencing D-KEFS Trails, Number-Letter Switching D-KEFS Color-Word Interference Test, Inhibition and Inhibition-Switching A Z score of 0 represents the sample mean. Higher composite Z scores r

Interventions

  • BEHAVIORAL Goal-focused Supportive Contact
  • BEHAVIORAL Motivationally Enhanced Compensatory Cognitive Training

Trial Details

FieldValue
Enrollment Target 193 participants
Start Date 2018-07-11
Est. Completion 2024-06-30
Phase NA
VA Office of Research and Development

1,668 total trials

What the finished NCT03225482 record still lists

NCT03225482 is an interventional study that assigns participants to a tested intervention. The registered 193 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 2 interventions - of which Goal-focused Supportive Contact is the first listed.

NCT03225482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03225482 about?

NCT03225482 is a clinical study titled "Cognitive Rehabilitation Therapy for Mild Cognitive Impairment". The number of older Veterans with Mild Cognitive Impairment (MCI) seeking care within the Veterans Affairs (VA) health care system is increasing and is expected to increase more rapidly as Vietnam era Veterans age. The cognitive effects of MCI and subsequent neurodegenerative disorders can adversely...

What is the current status of trial NCT03225482?

This trial is currently completed. It is a NA study. The enrollment target is 193 participants. The study started on 2018-07-11. Estimated completion is 2024-06-30.

What interventions are being tested in trial NCT03225482?

The interventions under investigation include: Goal-focused Supportive Contact (BEHAVIORAL), Motivationally Enhanced Compensatory Cognitive Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT03225482?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03225482's enrollment target sits among peer trials

193 569th of 2000 higher than 1,431 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03225482, the US trial registry maintained by the National Library of Medicine. NCT03225482 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.