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NCT03449576 · ClinicalTrials.gov registry record · NA
Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD
A NA study, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 69
- Enrollment target
NCT03449576: Completed NA study, sponsored by VA Office of Research and Development.
NCT03449576 is a NA study that has completed, run by VA Office of Research and Development. The registered enrollment target is 69 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03449576, a NA study, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 69 participants
- Enrollment target
Study Summary
Social difficulties are serious and frequent complicating factors in the treatment of post-traumatic stress disorder (PTSD). To better understand how treatment of post-traumatic stress disorder impacts neural mechanisms of social cognition, the investigators are examining behavior and brain processes associated with response to Trauma Management Therapy. Understanding the behavioral and neural impact of psychotherapy may contribute to development of more effective treatments for PTSD.
Primary Outcome
The Clinician-Administered PTSD Scale for DSM-5 (CAPS-5; Weathers et al. 2013; 2017) is a 20 item semi-structured instrument for the diagnosis and assessment of severity of posttraumatic stress disorder (PTSD). Each DSM-5 item is rated on a 0 (absent) to 4 (extreme/incapacitating) scale, and total score is calculated by summing severity scores across items. Total CAPS-5 severity can range from 0 to 80. \[edited 2/24/24: Higher scores mean a worse outcome.\]
Interventions
- OTHER Trauma Management Therapy
- OTHER Exposure Therapy with Psychotherapy group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 69 participants |
| Start Date | 2019-01-01 |
| Est. Completion | 2022-07-01 |
| Phase | NA |
What the finished NCT03449576 record still lists
NCT03449576 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 69 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Trauma Management Therapy is the first listed.
NCT03449576 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03449576 about?
NCT03449576 is a clinical study titled "Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD". Social difficulties are serious and frequent complicating factors in the treatment of post-traumatic stress disorder (PTSD). To better understand how treatment of post-traumatic stress disorder impacts neural mechanisms of social cognition, the investigators are examining behavior and brain processe...
What is the current status of trial NCT03449576?
This trial is currently completed. It is a NA study. The enrollment target is 69 participants. The study started on 2019-01-01. Estimated completion is 2022-07-01.
What interventions are being tested in trial NCT03449576?
The interventions under investigation include: Trauma Management Therapy (OTHER), Exposure Therapy with Psychotherapy group (OTHER).
Who is sponsoring clinical trial NCT03449576?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03449576's enrollment target sits among peer trials
69 1133rd of 2000 higher than 868 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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