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NCT03641924 · ClinicalTrials.gov registry record

Cognition and Psychotherapy in PTSD

A clinical trial, sponsored by VA Office of Research and Development.

Completed
Registry status
110
Enrollment target

NCT03641924: Completed study, sponsored by VA Office of Research and Development.

NCT03641924 is a clinical trial that has completed, run by VA Office of Research and Development. The registered enrollment target is 110 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03641924 has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
110 participants
Enrollment target

Study Summary

Posttraumatic stress disorder (PTSD) is prevalent among combat Veterans and is a substantial public health burden. Several psychotherapies, including cognitive processing therapy (CPT) and prolonged exposure therapy, have been recommended as efficacious for the treatment of PTSD and are being disseminated nationally in the VA Healthcare System. Yet many individuals show limited benefit from such treatments. Accumulating evidence indicates that episodic memory deficits may be one factor limiting psychotherapy treatment efficacy in PTSD. The proposed study will determine whether verbal memory is a specific predictor of CPT outcomes in PTSD, including both symptom reductions and functional outcomes. The study will also determine the pathways by which memory functioning affects treatment outcomes by examining relationships between memory functioning, treatment engagement, recall of treatment content, and illness course. More specifically, analyses will examine whether memory for treatment content affects the relationship between memory functioning and treatment outcomes.

Primary Outcome

PTSD Symptoms. The range of the scale is from 0 (no symptoms) to 80 (maximal symptoms). Higher scores corresponds to more symptoms.

Interventions

  • BEHAVIORAL Cognitive Processing Therapy

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2019-05-20
Est. Completion 2023-09-29
VA Office of Research and Development

1,668 total trials

What the finished NCT03641924 record still lists

NCT03641924 is an observational study that tracks outcomes without assigning an intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 1 intervention - of which Cognitive Processing Therapy is the first listed.

NCT03641924 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03641924 about?

NCT03641924 is a clinical study titled "Cognition and Psychotherapy in PTSD". Posttraumatic stress disorder (PTSD) is prevalent among combat Veterans and is a substantial public health burden. Several psychotherapies, including cognitive processing therapy (CPT) and prolonged exposure therapy, have been recommended as efficacious for the treatment of PTSD and are being dissem...

What is the current status of trial NCT03641924?

This trial is currently completed. The enrollment target is 110 participants. The study started on 2019-05-20. Estimated completion is 2023-09-29.

What interventions are being tested in trial NCT03641924?

The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT03641924?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03641924, the US trial registry maintained by the National Library of Medicine. NCT03641924 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.