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NCT03790657 · ClinicalTrials.gov registry record · Phase 1

CONTROL Walking Study

A Phase 1 study, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 1
Development phase
72
Enrollment target

NCT03790657: Completed Phase 1 study, sponsored by VA Office of Research and Development.

NCT03790657 is a Phase 1 study that has completed, run by VA Office of Research and Development. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03790657, a Phase 1 study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 1
Development phase
72 participants
Enrollment target

Study Summary

Older adults often experience substantial deficits in walking ability, especially for walking tasks that are more complex such as obstacle crossing. This is due in part to changes in the brain that make performance of physical and cognitive tasks more difficult. Rehabilitation can help to improve walking ability, but effective rehabilitation is time consuming and expensive. New approaches are needed to improve the efficiency of rehabilitation so that gains in walking ability are widely attainable. A promising strategy is to focus on enhancing motor learning, which is defined as improved ability to perform a motor task due to practice or experience. The investigators will investigate the use of non-invasive brain stimulation to increase motor learning and retention of the newly learned walking skills. The investigators will also use neuroimaging to assess brain characteristics that explain how motor learning works. The knowledge gained from this study is expected to contribute to better understanding of mechanistic targets and intervention approaches to improve rehabilitation of walking.

Primary Outcome

Change in the fastest safe walking speed over a complex walking course

Interventions

  • BEHAVIORAL practice of a complex walking task
  • DEVICE Active transcranial direct current stimulation (Active tDCS)
  • DEVICE Sham transcranial direct current stimulation (Sham tDCS)

Trial Details

FieldValue
Enrollment Target 72 participants
Start Date 2019-08-01
Est. Completion 2024-08-01
Phase Phase 1
VA Office of Research and Development

1,668 total trials

What the finished NCT03790657 record still lists

NCT03790657 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).

The record links to 0 conditions, and to 3 interventions - of which practice of a complex walking task is the first listed.

NCT03790657 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03790657 about?

NCT03790657 is a clinical study titled "CONTROL Walking Study". Older adults often experience substantial deficits in walking ability, especially for walking tasks that are more complex such as obstacle crossing. This is due in part to changes in the brain that make performance of physical and cognitive tasks more difficult. Rehabilitation can help to improve wa...

What is the current status of trial NCT03790657?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2019-08-01. Estimated completion is 2024-08-01.

What interventions are being tested in trial NCT03790657?

The interventions under investigation include: practice of a complex walking task (BEHAVIORAL), Active transcranial direct current stimulation (Active tDCS) (DEVICE), Sham transcranial direct current stimulation (Sham tDCS) (DEVICE).

Who is sponsoring clinical trial NCT03790657?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03790657's enrollment target sits among peer trials

72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03790657, the US trial registry maintained by the National Library of Medicine. NCT03790657 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.