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NCT07430761 · ClinicalTrials.gov registry record
ET Stigma Response to Tremor Suppression
A clinical trial of Stigma, Social and Action Tremor, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- 220
- Enrollment target
- 1
- Study location
NCT07430761: Recruiting study of Stigma, Social and Action Tremor, sponsored by University of Texas Southwestern Medical Center.
NCT07430761 is a study of Stigma, Social and Action Tremor that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 220 participants, below the 616-participant average among 10 other Stigma, Social trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07430761, a study of Stigma, Social and Action Tremor, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- 220 participants
- Enrollment target
- 1
- Study location
Study Summary
Essential Tremor (ET) is prevalent, affecting approximately 3% of the adult population. Involuntary shaking of the hands during action is a prominent feature, interfering with feeding and writing and other manual tasks. The involuntary movement is visible to observers, some of whom misinterpret the shakiness as manifestation of anxiety or instability, while some other observers attribute it to alcohol or drug use. The psychological effects of resulting stigma on quality of life for people with ET can rival the physical difficulties caused by the condition. For this study, we propose to measure 1 year after effective tremor suppression following thalamotomy with high intensity focused ultrasound changes from baseline in psychological distress and social dysfunction related to ET stigma, and to correlate change from baseline with improvement in functional status related to tremor and in objective measures of tremor severity. We hope to discover that ET stigma is largely reversible when tremor is effectively treated, and we aim to learn what degree of tremor suppression correlates with substantial psychological relief. We will also determine if ET stigma is predominantly helped by unilateral dominant-hand treatment, or if the second side treatment is necessary to accomplish most benefit.
Primary Outcome
Psychological distress related to other people's reaction to their tremor.
Conditions Studied
Interventions
- PROCEDURE stereotactic thalamotomy with focused ultrasound
Study Locations (1)
Texas
- University of Texas Soouthwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2025-01-01 |
| Est. Completion | 2027-08-30 |
What NCT07430761 shows while recruiting
NCT07430761 is an observational study that tracks outcomes without assigning an intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, below the 616-participant average among 10 other Stigma, Social trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Stigma, Social appearing as the primary indexed condition, and to 1 intervention - of which stereotactic thalamotomy with focused ultrasound is the first listed.
NCT07430761 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07430761 about?
NCT07430761 is a clinical study titled "ET Stigma Response to Tremor Suppression". Essential Tremor (ET) is prevalent, affecting approximately 3% of the adult population. Involuntary shaking of the hands during action is a prominent feature, interfering with feeding and writing and other manual tasks. The involuntary movement is visible to observers, some of whom misinterpret the ...
What is the current status of trial NCT07430761?
This trial is currently recruiting. The enrollment target is 220 participants. The study started on 2025-01-01. Estimated completion is 2027-08-30.
What conditions does trial NCT07430761 study?
This clinical trial studies the following conditions: Stigma, Social, Action Tremor.
What interventions are being tested in trial NCT07430761?
The interventions under investigation include: stereotactic thalamotomy with focused ultrasound (PROCEDURE).
Who is sponsoring clinical trial NCT07430761?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07430761 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07430761's enrollment target sits among peer trials
220 6th of 10 higher than 5 of 10 other Stigma, Social trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stigma, Social trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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