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NCT07100847 · ClinicalTrials.gov registry record · Phase 1
Periprostatic Neurolysis in Prostate Cancer
A Phase 1 study of Prostate Cancer and NERVES, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
- 1
- Study location
NCT07100847 is a Phase 1 study of Prostate Cancer and NERVES that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 21 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07100847, a Phase 1 study of Prostate Cancer and NERVES, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to assess whether inhibiting nerve activity to the prostate delays progression of disease in men with high-risk clinical features for prostate cancer. Prostate cancer has been shown to invade nerves, a mechanism that is thought to be involved in prostate cancer spread in men with high-risk cancer. When nerve activity to the prostate is blocked in mice with prostate cancer, prostate cancer growth and spread are inhibited. In a previous study we showed that doing so in humans was safe and may have anticancer therapeutic effect. In this study we will test whether one versus two injections of nerve blocking agent is more effective at reducing nerves in the prostate and whether it will slow/stop spread of prostate cancer after treatment.
Conditions Studied
Interventions
- PROCEDURE Periprostatic neurolysis with dehydrated alcohol (ethanol)
Study Locations (1)
Texas
- University of Texas Southwestern Medical Center - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2025-08-15 |
| Est. Completion | 2028-08 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07100847
The ClinicalTrials.gov registry entry for NCT07100847 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (97% lower). The listed sponsor is University of Texas Southwestern Medical Center, which has 837 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention - of which Periprostatic neurolysis with dehydrated alcohol (ethanol) is the first listed.
NCT07100847 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT07100847 about?
NCT07100847 is a clinical study titled "Periprostatic Neurolysis in Prostate Cancer". The purpose of this research study is to assess whether inhibiting nerve activity to the prostate delays progression of disease in men with high-risk clinical features for prostate cancer. Prostate cancer has been shown to invade nerves, a mechanism that is thought to be involved in prostate cancer ...
What is the current status of trial NCT07100847?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2025-08-15. Estimated completion is 2028-08.
What conditions does trial NCT07100847 study?
This clinical trial studies the following conditions: Prostate Cancer, NERVES, Neurobiology OF Cancer, NEUROLYSIS.
What interventions are being tested in trial NCT07100847?
The interventions under investigation include: Periprostatic neurolysis with dehydrated alcohol (ethanol) (PROCEDURE).
Who is sponsoring clinical trial NCT07100847?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07100847 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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