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NCT07387666 · ClinicalTrials.gov registry record · Early Phase 1
Imaging Acetadote Metabolism in Glioblastoma
A Early Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 10
- Enrollment target
NCT07387666: Recruiting Early Phase 1 study, sponsored by University of Texas Southwestern Medical Center.
NCT07387666 is a Early Phase 1 study that is actively recruiting participants, run by University of Texas Southwestern Medical Center. The registered enrollment target is 10 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07387666, a Early Phase 1 study, is actively recruiting participants, sponsored by University of Texas Southwestern Medical Center.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
This goal of this clinical trial is to evaluate how Acetadote affects metabolism in patients with glioblastoma. Drugs like Acetadote, which affect the level of damage in a cell (oxidative stress), may impact brain tumor metabolism and slow the growth of brain tumors. The investigators are evaluating how Acetadote affects glioblastoma metabolism by using MRI-based methods and by determining the changes in metabolism in brain tumor tissue resected from patients with a new diagnosis of glioblastoma.
Primary Outcome
The effect of Acetadote on glioblastoma metabolism will be assessed by measuring cysteine, glutathione, and lactate in glioblastoma through MRS.
Interventions
- DRUG Acetadote
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-06-18 |
| Est. Completion | 2028-07-01 |
| Phase | Early Phase 1 |
What NCT07387666 shows while recruiting
NCT07387666 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (81% lower).
The record links to 0 conditions, and to 1 intervention - of which Acetadote is the first listed.
NCT07387666 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07387666 about?
NCT07387666 is a clinical study titled "Imaging Acetadote Metabolism in Glioblastoma". This goal of this clinical trial is to evaluate how Acetadote affects metabolism in patients with glioblastoma. Drugs like Acetadote, which affect the level of damage in a cell (oxidative stress), may impact brain tumor metabolism and slow the growth of brain tumors. The investigators are evaluatin...
What is the current status of trial NCT07387666?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 10 participants. The study started on 2026-06-18. Estimated completion is 2028-07-01.
What interventions are being tested in trial NCT07387666?
The interventions under investigation include: Acetadote (DRUG).
Who is sponsoring clinical trial NCT07387666?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07387666's enrollment target sits among peer trials
10 1629th of 2000 higher than 256 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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