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NCT05505084 · ClinicalTrials.gov registry record

Alveolar Ridge Preservation Following Tooth Extraction.

A clinical trial of Caries and Tooth Extraction Status Nos, sponsored by University of Pennsylvania.

Active
Registry status
50
Enrollment target
1
Study location

NCT05505084 is a study of Caries and Tooth Extraction Status Nos that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 50 participants, roughly in line with the 53-participant average among 7 other Caries trials with a reported enrollment target. The trial reports 1 study location across 1 state.

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The verdict

NCT05505084, a study of Caries and Tooth Extraction Status Nos, is active but no longer recruiting, sponsored by University of Pennsylvania.

ACTIVE NOT RECRUITING
Registry status
50 participants
Enrollment target
1
Study location

Study Summary

Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies. Especially during the first three months followed by the tooth extraction, the volume of bone may change significantly without any interference. Thus, doing a ridge preservation procedure following the extraction is a common standard of care method to maintain the socket volume if implant placement is considered as a treatment option in the future. A variety of materials and methods have been used for ridge preservation. However, it's still inconclusive to determine the best material to maintain the ridge dimension, especially for membrane placement that allows for space maintenance to protect the grafting material. Furthermore, there is no evidence to show any treatment rationale is superior to any other ridge preservation method. In general, the membrane serves the function of the barrier and space protector. The periodontal surgeon use membranes to exclude the epithelium growth and to limit the collapse of the soft tissue into the healing alveolar socket. Regarding resorbable and non-resorbable membrane materials, both serve the function of protecting the graft material from the oral cavity. However, there are also many demonstrating that without membranes the extraction socket healed nicely without any interferences. The question to us is: Do we need the membrane to exclude the epithelium or any kind of surgical dressing material is sufficient enough to preserve the volume of the extracted ridge? The object of this study is to compare five popular membranes on the market that present different characteristics of the membranes.

Interventions

  • PROCEDURE Tooth extraction and ridge preservation using different barrier mermbranes

Study Locations (1)

Pennsylvania

  • Penn Dental Medicine - Philadelphia

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2022-08-15
Est. Completion 2025-12-31

Sponsor

University of Pennsylvania

1,423 total trials

What the Registry Record Tells You About NCT05505084

The ClinicalTrials.gov registry entry for NCT05505084 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 53-participant average among 7 other Caries trials with a reported enrollment target. The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Caries appearing as the primary indexed condition, and to 1 intervention - of which Tooth extraction and ridge preservation using different barrier mermbranes is the first listed.

NCT05505084 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05505084 about?

NCT05505084 is a clinical study titled "Alveolar Ridge Preservation Following Tooth Extraction.". Bone resorption after a tooth extraction is a generally accepted knowledge and has been demonstrated by many animal and human studies. Especially during the first three months followed by the tooth extraction, the volume of bone may change significantly without any interference. Thus, doing a ridge ...

What is the current status of trial NCT05505084?

This trial is currently active not recruiting. The enrollment target is 50 participants. The study started on 2022-08-15. Estimated completion is 2025-12-31.

What conditions does trial NCT05505084 study?

This clinical trial studies the following conditions: Caries, Tooth Extraction Status Nos, Tooth Fractures.

What interventions are being tested in trial NCT05505084?

The interventions under investigation include: Tooth extraction and ridge preservation using different barrier mermbranes (PROCEDURE).

Who is sponsoring clinical trial NCT05505084?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05505084 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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