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NCT05823766 · ClinicalTrials.gov registry record
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
A clinical trial of Traumatic Brain Injury and Post-traumatic Epilepsy, sponsored by University of Pennsylvania.
- Active
- Registry status
- 300
- Enrollment target
- 9
- Study locations
NCT05823766: Active study of Traumatic Brain Injury and Post-traumatic Epilepsy, sponsored by University of Pennsylvania.
NCT05823766 is a study of Traumatic Brain Injury and Post-traumatic Epilepsy that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 300 participants, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target. The trial reports 9 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05823766, a study of Traumatic Brain Injury and Post-traumatic Epilepsy, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 9
- Study locations
Study Summary
The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12 months after injury.
Primary Outcome
The GOSE provides an overall measure of functional status based on information on cognition, independence, employability, and social/community participation collected via structured interview. Individuals are described by one of the eight outcome categories: Dead (1); Vegetative State (2); Lower Severe Disability (3); Upper Severe Disability (4); Lower Moderate Disability (5); Upper Moderate Disability (6); Lower Good Recovery (7) and Upper Good Recovery (8). Good Recovery is defined as a score
Conditions Studied
Interventions
- PROCEDURE Blood Draw
- BEHAVIORAL In-Person Outcome Assessment
- PROCEDURE 3T Magnetic Resonance Imaging (MRI)
- BEHAVIORAL Clinical Visit
- PROCEDURE EEG
Study Locations (9)
Texas
- University of Texas at Austin - Austin
- University of Texas Southwestern - Dallas
- Baylor College of Medicine - Houston
Pennsylvania
- University of Pennsylvania/Penn Presbyterian Medical Center - Philadelphia
- University of Pittsburgh - Pittsburgh
California
- University of California, San Francisco - San Francisco
Massachusetts
- Spaulding Rehabilitation Hospital - Charlestown
Ohio
- University of Cincinnati - Cincinnati
Washington
- University of Washington - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2022-03-01 |
| Est. Completion | 2027-02 |
What the registry record for NCT05823766 still lists
NCT05823766 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 276-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target.
The record links to 2 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 5 interventions - of which Blood Draw is the first listed.
NCT05823766 lists 9 locations in 6 states (Texas, Pennsylvania, California).
Frequently Asked Questions
What is clinical trial NCT05823766 about?
NCT05823766 is a clinical study titled "Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)". The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12 months after injury.
What is the current status of trial NCT05823766?
This trial is currently active not recruiting. The enrollment target is 300 participants. The study started on 2022-03-01. Estimated completion is 2027-02.
What conditions does trial NCT05823766 study?
This clinical trial studies the following conditions: Traumatic Brain Injury, Post-traumatic Epilepsy.
What interventions are being tested in trial NCT05823766?
The interventions under investigation include: Blood Draw (PROCEDURE), In-Person Outcome Assessment (BEHAVIORAL), 3T Magnetic Resonance Imaging (MRI) (PROCEDURE), Clinical Visit (BEHAVIORAL), EEG (PROCEDURE).
Who is sponsoring clinical trial NCT05823766?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05823766 being conducted?
This trial has 9 study locations across California, Massachusetts, Ohio, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Traumatic Brain Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05823766's enrollment target sits among peer trials
300 20th of 171 higher than 146 of 171 other Traumatic Brain Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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