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NCT07132788 · ClinicalTrials.gov registry record
Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass
A clinical trial of Pulmonary Hypertension, sponsored by University of Pennsylvania.
- Active
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT07132788: Active study of Pulmonary Hypertension, sponsored by University of Pennsylvania.
NCT07132788 is a study of Pulmonary Hypertension that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 150 participants, below the 612-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07132788, a study of Pulmonary Hypertension, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with pulmonary arterial hypertension (PAH) are at increased risk of muscle loss and decreased physical activity. This study will aim to (1) understand the way in which muscle loss occurs in PAH, particularly the role of fat surrounding the heart, and (2) look at the impact muscle loss has on quality of life, daily physical activity, and hospitalizations in patients with PAH. The findings from this study could help identify potentially treatable factors that may improve the overall quality of life and physical functioning of patients with PAH. Subjects will be asked to attend a baseline visit where the following will be performed: * Measure your vital signs * Undergo a research blood draw, less than 4 tablespoons * Provide a urine pregnancy test (if applicable) * Review demographics, personal history, and medical history * Review current PAH medications * Complete questionnaires on how your PAH affects you * Complete a test of physical performance * Complete a grip strength test * Undergo an echocardiogram (Echo) * Complete a six-minute walk test * Undergo a Chest CT Scan * Undergo a scan of your body composition (DXA scan) * Obtain a weight and body composition measurement on the InBody Scale Subjects will also complete activity moniotring, two 24-hour diet recalls, and participate in remote follow-up visits every 6 months
Primary Outcome
Adequacy of micronutrient and protein intake are derived from the two 24 hour diets recalls.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST blood draw
- DIAGNOSTIC_TEST Short Performance Physical Battery
- DIAGNOSTIC_TEST Grip strength test
- DIAGNOSTIC_TEST Six minute walk test
- RADIATION Chest CT scan
Study Locations (1)
Pennsylvania
- University of Pennsylvania Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2029-09-30 |
What the registry record for NCT07132788 still lists
NCT07132788 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 612-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Pulmonary Hypertension appearing as the primary indexed condition, and to 5 interventions - of which blood draw is the first listed.
NCT07132788 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07132788 about?
NCT07132788 is a clinical study titled "Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass". Patients with pulmonary arterial hypertension (PAH) are at increased risk of muscle loss and decreased physical activity. This study will aim to (1) understand the way in which muscle loss occurs in PAH, particularly the role of fat surrounding the heart, and (2) look at the impact muscle loss has o...
What is the current status of trial NCT07132788?
This trial is currently active not recruiting. The enrollment target is 150 participants. The study started on 2025-05-01. Estimated completion is 2029-09-30.
What conditions does trial NCT07132788 study?
This clinical trial studies the following conditions: Pulmonary Hypertension.
What interventions are being tested in trial NCT07132788?
The interventions under investigation include: blood draw (DIAGNOSTIC_TEST), Short Performance Physical Battery (DIAGNOSTIC_TEST), Grip strength test (DIAGNOSTIC_TEST), Six minute walk test (DIAGNOSTIC_TEST), Chest CT scan (RADIATION).
Who is sponsoring clinical trial NCT07132788?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07132788 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07132788's enrollment target sits among peer trials
150 26th of 72 higher than 47 of 72 other Pulmonary Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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