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NCT06266390 · ClinicalTrials.gov registry record · NA
Individualized (fMRI-guided) TMS Treatment for Depression
A NA study of Depression and Major Depressive Disorder, sponsored by University of Pennsylvania.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06266390 is a NA study of Depression and Major Depressive Disorder that is active but no longer recruiting, run by University of Pennsylvania. The registered enrollment target is 50 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06266390, a NA study of Depression and Major Depressive Disorder, is active but no longer recruiting, sponsored by University of Pennsylvania.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression. Specifically, investigators aim to determine whether the sgACC is engaged when TMS is delivered to specific targets and if the engagement of sgACC changes throughout a full TMS treatment intervention. To achieve this goal, the investigators will employ a combination of TMS and Magnetic Resonance Imaging (MRI) procedures. Study participation will include completing various questionnaires, clinical assessments, receiving a full transcranial magnetic stimulation (TMS) treatment intervention (every weekday for 6 weeks), and undergoing MRI scans, both with and without concurrent TMS.
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation (TMS)
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-05-29 |
| Est. Completion | 2026-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06266390
The ClinicalTrials.gov registry entry for NCT06266390 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (94% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation (TMS) is the first listed.
NCT06266390 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06266390 about?
NCT06266390 is a clinical study titled "Individualized (fMRI-guided) TMS Treatment for Depression". The purpose of this study is to investigate the responses of the brain region known as the subgenual anterior cingulate cortex (sgACC) during transcranial magnetic stimulation (TMS) in individuals with depression. Specifically, investigators aim to determine whether the sgACC is engaged when TMS is ...
What is the current status of trial NCT06266390?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-05-29. Estimated completion is 2026-06.
What conditions does trial NCT06266390 study?
This clinical trial studies the following conditions: Depression, Major Depressive Disorder, Persistent Depressive Disorder.
What interventions are being tested in trial NCT06266390?
The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) (DEVICE).
Who is sponsoring clinical trial NCT06266390?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06266390 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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