University of California, Irvine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of California, Irvine sits in the top decile of US sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count).

368 total trials 74 currently recruiting 228 completed early-phase tilt top decile by trial count

University of California, Irvine: 368 sponsored US clinical trials, 74 recruiting.

University of California, Irvine sponsors 368 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 228 completed. 27 of these trials are in Phase 3-4 (later-stage) and 92 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Cancer, with 6 trials.

Top-decile sponsor footprint

University of California, Irvine ranks in the top decile of sponsors by registered trial count (#96 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

228 of 258 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

368 total, page 4 of 8

COMPLETED NA

The NUTRIENT Trial (NUTRitional Intervention Among myEloproliferative Neoplasms): Feasibility Phase

NCT03907436

TERMINATED Phase 4

Enhancing Memory Consolidation in Older Adults

NCT03657212

COMPLETED NA

Long-term Telerehabilitation for Patients With Stroke

NCT03460587

COMPLETED NA

Screening TO Prevent ColoRectal Cancer (STOP CRC) Among At-Risk Chinese and Korean American Primary Care Patients

NCT03481296

COMPLETED NA

Wearable Device for Motivating Hand Use After Stroke

NCT03084705

COMPLETED NA

Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications

NCT04851314

COMPLETED Early Phase 1

Fecal Microbiota Transplantation for the Treatment of Recurrent Urinary Tract Infections

NCT03050515

TERMINATED NA

Energy Devices for Rejuvenation

NCT03767972

COMPLETED NA

Dietary Approaches for Cardiometabolic Health

NCT03527290

COMPLETED NA

Postoperative Opioid Consumption After Urogyneocologic Surgery

NCT03586219

COMPLETED

Ethnic Influences on Stress, Energy Balance and Obesity in Adolescents

NCT03369691

COMPLETED NA

Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects

NCT03370393

COMPLETED Early Phase 1

The Utility of Platelet Rich Plasma in Hair Loss

NCT03376581

COMPLETED NA

Maternal Emotions and Diet in Pregnancy

NCT03278392

TERMINATED NA

Fractional Photothermolysis for Hair Follicle Induction

NCT03382184

COMPLETED Phase 4

Functional Effects of Botox on the Brain Using MRS and fMRI

NCT03373162

TERMINATED NA

Evaluating the Efficacy of the Melanocyte Keratinocyte Transplantation Procedure in the Treatment of Vitiligo

NCT04374435

COMPLETED Phase 2

Nicotinamide as an Early Alzheimer's Disease Treatment

NCT03061474

COMPLETED Phase 4

Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment

NCT03229889

COMPLETED Phase 2

Safety and Efficacy of Fenofibrate as a Treatment for Huntington's Disease

NCT03515213

COMPLETED Phase 4

Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization

NCT03118232

COMPLETED Phase 2

Effectiveness of Onabotulinumtoxin A (Botox) in Pediatric Patients Experiencing Migraines: A Study in the Pediatric Pain Population

NCT03055767

COMPLETED NA

Emotional Response in Psychiatric and Control Participants

NCT03056781

COMPLETED NA

Efficacy Study of the LARA Wheelchair System for Subacute Stroke Patients

NCT02830893

COMPLETED NA

Comparison of Nifedipine Versus Indomethacin for Acute Preterm Labor

NCT03129945

COMPLETED NA

HOPE Social Media Intervention for HIV Testing and Studying Social Networks

NCT02944877

COMPLETED NA

Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder

NCT03003221

COMPLETED NA

Physical Exercise to Reduce Anxiety in Underserved Children With ASD

NCT02902952

COMPLETED Phase 2

Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit)

NCT02823028

COMPLETED NA

Gas Exchange Kinetics and Work Load During Exercise

NCT03770507

COMPLETED NA

Safety and Effectiveness of Resistance Exercise Training in Patients With Pompe Disease.

NCT02654886

COMPLETED Phase 1

Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke

NCT02360488

COMPLETED Early Phase 1

Assessing the Effects of Tretinoin Cream on Human Skin With Optical Imaging Technologies

NCT02410980

COMPLETED

Investigating Pompe Prevalence in Neuromuscular Medicine Academic Practices

NCT02838368

COMPLETED NA

Immune-Related Trafficking and Signaling in Human Skin Associated With Low-Power, Infrared Laser Treatment

NCT02453113

COMPLETED NA

Pilot Study of Percutaneous Posterior Tibial Nerve Stimulation for the Treatment of IC/PBS

NCT02550561

COMPLETED

Predicting Neoadjuvant Chemotherapy Response by Using a Combined MRI and Scinti-Mammography (MRI-SMM) System

NCT02690805

COMPLETED Phase 4

Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses

NCT03327831

COMPLETED NA

Efficacy Study of the Music Glove Patients With Spinal Cord Injuries

NCT02473614

COMPLETED NA

Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?

NCT02276495

COMPLETED Early Phase 1

The EMPATHy Toolkit: Helping Diabetes Patients Overcome Barriers to Medication Adherence

NCT02324036

COMPLETED NA

Ovarian Cancer Patient-Centered Decision Aid

NCT02259699

COMPLETED

A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women

NCT02527018

COMPLETED

A Clinical and Imaging Study to Evaluate a Novel Dentifrice

NCT02271815

COMPLETED NA

Multi-Center Comparison of Dual Lumen Versus Single Lumen Ureteroscopes

NCT02123082

COMPLETED Phase 1

Heated Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT02199171

COMPLETED

Comparing Pleth Variability Index (PVI) Measurements at Different Sensing Locations

NCT02124551

COMPLETED

Fecal Microbiota Transplant for Recurrent Clostridium Difficile Infection

NCT02326636

COMPLETED NA

Active Bathing to Eliminate Infection (ABATE Infection) Trial

NCT02063867

COMPLETED NA

Patient Centered Quality Reporting

NCT02738320

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Phase Distribution

PhaseTrial count
Phase 1 46
Phase 2 46
Phase 3 6
Phase 4 21

What is open in the University of California, Irvine pipeline

74 recruiting of 368 indexed (20% open); 228 completed (62%).

Phase mix: 27 late (III/IV) vs 92 early (I/II) (early-phase heavy).

Top condition: Cancer (6 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of California, Irvine: open-pipeline peers nationwide

Peers matched on 368 registered trials and 20% open enrollment, not the therapeutic-area sidebar.

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%5%10%15%20%25% Total trials Recruiting share University of California, IrvineNorthwell HealthUNC Lineberger Comprehensive Cancer CenterRoswell Park Cancer InstituteNew York State Psychiatric InstituteUniversity of MiamiEndeavor HealthAcera SurgicalAlign Technology
University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of California, Irvine sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 368 trials (± recruiting share)

Sponsors near 20% open enrollment (± trial volume)

What to do with this University of California, Irvine page

368 registered trials is a research-attention snapshot, not an endorsement of University of California, Irvine or any single study.

  • 74 of University of California, Irvine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Cancer is the condition University of California, Irvine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of California, Irvine pipeline card: 368 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.