Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05555342 · ClinicalTrials.gov registry record · Early Phase 1

A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm

A Early Phase 1 study of Metastatic Cancer and Lung Tumor, sponsored by University of California, Irvine.

Completed
Registry status
Early Phase 1
Development phase
6
Enrollment target
1
Study location

NCT05555342: Completed Early Phase 1 study of Metastatic Cancer and Lung Tumor, sponsored by University of California, Irvine.

NCT05555342 is a Early Phase 1 study of Metastatic Cancer and Lung Tumor that has completed, run by University of California, Irvine. The registered enrollment target is 6 participants, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05555342, a Early Phase 1 study of Metastatic Cancer and Lung Tumor, has completed, sponsored by University of California, Irvine.

COMPLETED
Registry status
Early Phase 1
Development phase
6 participants
Enrollment target
1
Study location

Study Summary

This is a phase 0, pilot prospective study to determine the feasibility of combined irreversible electroporation (IRE) and radiation therapy in subjects with lung tumors with metastatic cancer of any histology. These are subjects who have advanced disease (stage IV) or previously treated disease that has become progressive, recurrent, or metastatic.

Primary Outcome

Number of patients completing treatment of both IRE and the single fraction of radiation. Up to 6 replacements are allowed (total subjects 6-12)

Interventions

  • RADIATION Radiation Therapy
  • PROCEDURE Irreversible electroporation (IRE) ablation

Study Locations (1)

California

  • Chao Family Comprehensive Cancer Center University of California, Irvine - Orange

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2023-01-03
Est. Completion 2024-10-27
Phase Early Phase 1
University of California, Irvine

368 total trials

What the finished NCT05555342 record still lists

NCT05555342 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 444-participant average among 109 other Metastatic Cancer trials with a reported enrollment target (99% lower).

The record links to 2 conditions, with Metastatic Cancer appearing as the primary indexed condition, and to 2 interventions - of which Radiation Therapy is the first listed.

NCT05555342 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05555342 about?

NCT05555342 is a clinical study titled "A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm". This is a phase 0, pilot prospective study to determine the feasibility of combined irreversible electroporation (IRE) and radiation therapy in subjects with lung tumors with metastatic cancer of any histology. These are subjects who have advanced disease (stage IV) or previously treated disease tha...

What is the current status of trial NCT05555342?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 6 participants. The study started on 2023-01-03. Estimated completion is 2024-10-27.

What conditions does trial NCT05555342 study?

This clinical trial studies the following conditions: Metastatic Cancer, Lung Tumor.

What interventions are being tested in trial NCT05555342?

The interventions under investigation include: Radiation Therapy (RADIATION), Irreversible electroporation (IRE) ablation (PROCEDURE).

Who is sponsoring clinical trial NCT05555342?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05555342 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Metastatic Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05555342's enrollment target sits among peer trials

6 107th of 109 higher than 2 of 109 other Metastatic Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Metastatic Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05555342, the US trial registry maintained by the National Library of Medicine. NCT05555342 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.