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NCT07178821 · ClinicalTrials.gov registry record · NA
Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD
A NA study, sponsored by University of California, Irvine.
- Not yet
- Registry status
- NA
- Development phase
- 120
- Enrollment target
NCT07178821 is a NA study that has not yet begun recruiting, run by University of California, Irvine. The registered enrollment target is 120 participants.
The verdict
NCT07178821, a NA study, has not yet begun recruiting, sponsored by University of California, Irvine.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
Study Summary
Peroral endoscopic myotomy (POEM) is an effective, minimally invasive treatment for achalasia, offering excellent rates of symptom relief. However, a significant drawback is the high incidence of gastroesophageal reflux disease (GERD) following the procedure. One proposed technical modification, the selective preservation of the sling fibers during gastric myotomy (SFP-POEM), may reduce this risk without compromising efficacy as compared to a conventional POEM procedure, which includes myotomy of the sling fibers. In this study, adults with achalasia will be randomly assigned to receive one of the two POEM technical approaches. Researchers will monitor whether preserving sling fibers reduces the rates of reflux esophagitis (classified as Los Angeles Grade B or higher) on follow-up endoscopy. Participants will be followed for up to 1 year after the procedure.
Interventions
- PROCEDURE Conventional POEM
- PROCEDURE Sling Fiber-Preserving POEM
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-12-01 |
| Est. Completion | 2028-01-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07178821
The ClinicalTrials.gov registry entry for NCT07178821 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Conventional POEM is the first listed.
NCT07178821 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07178821 about?
NCT07178821 is a clinical study titled "Sling-Fiber Preservation POEM vs. Conventional POEM for Reducing Post-POEM GERD". Peroral endoscopic myotomy (POEM) is an effective, minimally invasive treatment for achalasia, offering excellent rates of symptom relief. However, a significant drawback is the high incidence of gastroesophageal reflux disease (GERD) following the procedure. One proposed technical modification, the...
What is the current status of trial NCT07178821?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-12-01. Estimated completion is 2028-01-01.
What interventions are being tested in trial NCT07178821?
The interventions under investigation include: Conventional POEM (PROCEDURE), Sling Fiber-Preserving POEM (PROCEDURE).
Who is sponsoring clinical trial NCT07178821?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
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