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NCT07281781 · ClinicalTrials.gov registry record · Phase 1

Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow

A Phase 1 study of Myelofibrosis and Myelofibrosis; Anemia, sponsored by University of California, Irvine.

Recruiting
Registry status
Phase 1
Development phase
10
Enrollment target
1
Study location

NCT07281781 is a Phase 1 study of Myelofibrosis and Myelofibrosis; Anemia that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 10 participants, below the 196-participant average among 61 other Myelofibrosis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07281781, a Phase 1 study of Myelofibrosis and Myelofibrosis; Anemia, is actively recruiting participants, sponsored by University of California, Irvine.

RECRUITING
Registry status
Phase 1
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

This is a phase I/II protocol investigating whether Nelfinavir can improve anemia and lower serum fibrosis biomarkers in Myelofibrosis patients.

Conditions Studied

Myelofibrosis Myelofibrosis; Anemia

Interventions

  • DRUG Nelfinavir

Study Locations (1)

California

  • Chao Family Comprehensive Cancer Center, University of California, Irvine - Orange

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-09-16
Est. Completion 2027-06
Phase Phase 1

Sponsor

University of California, Irvine

368 total trials

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What the Registry Record Tells You About NCT07281781

The ClinicalTrials.gov registry entry for NCT07281781 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 196-participant average among 61 other Myelofibrosis trials with a reported enrollment target (95% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Myelofibrosis appearing as the primary indexed condition, and to 1 intervention - of which Nelfinavir is the first listed.

NCT07281781 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07281781 about?

NCT07281781 is a clinical study titled "Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow". This is a phase I/II protocol investigating whether Nelfinavir can improve anemia and lower serum fibrosis biomarkers in Myelofibrosis patients.

What is the current status of trial NCT07281781?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2025-09-16. Estimated completion is 2027-06.

What conditions does trial NCT07281781 study?

This clinical trial studies the following conditions: Myelofibrosis, Myelofibrosis; Anemia.

What interventions are being tested in trial NCT07281781?

The interventions under investigation include: Nelfinavir (DRUG).

Who is sponsoring clinical trial NCT07281781?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07281781 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.