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NCT06821178 · ClinicalTrials.gov registry record · NA
My Life and My Experiences Project
A NA study of Stress and Memory in Adolescence, sponsored by University of California, Irvine.
- Recruiting
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 1
- Study location
NCT06821178: Recruiting NA study of Stress and Memory in Adolescence, sponsored by University of California, Irvine.
NCT06821178 is a NA study of Stress and Memory in Adolescence that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 400 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06821178, a NA study of Stress and Memory in Adolescence, is actively recruiting participants, sponsored by University of California, Irvine.
- RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Child maltreatment is one of the most formidable public health crises in the United States, affecting millions of youth each year. The adverse consequences of maltreatment for youth, as well as for their families and entire communities, are pervasive, costly, and enduring. To intervene and reduce these consequences, it is imperative that victims provide clear and accurate accounts of their prior experiences. Currently, considerable skepticism exists regarding maltreated youth's ability to provide such accounts, especially for experiences that were stressful, leading to youths' reports being challenged or not believed. It is possible that this skepticism is unwarranted, and maltreated youth actually demonstrate better memory than their non-maltreated counterparts, but only for stressful salient personal experiences. This project will ethically and rigorously test this possibility via a short-term longitudinal experimental investigation that compares the effects of acute stress on memory between maltreated and demographically matched non-maltreated 12-17-year-olds. In an initial in-person session, youth will be randomly assigned (equal maltreated and non-maltreated youth across age) to complete standardized salient personal activities that are experimentally manipulated to vary in whether they induce higher or lower levels of acute stress. Immediately afterward, youth will complete an encoding task comprised of positive, negative, and neutral images. In subsequent sessions (two remote and one in person) spanning approximately one month, youth's memory will be tested for the images via a recognition task asking them to discriminate previously seen from unseen images and for the personal activities via recall and direct questions that probe for the extent and accuracy of memory. Youth's rumination about the personal activities will also be measured. The project's main hypothesis is that maltreatment will lead to particularly robust memory for the personal activities, bu
Primary Outcome
This memory measure reflects how well participants remember images that they encoded in Session 1. Participants are presented with previously seen and unseen images. Their job is to discriminate the two (i.e., say "old" for prior images and "new" for unseen images). Scores computed based on their responses include discriminability and response bias tendencies. These scores will be examined in relation to participants' maltreatment status and whether they encoded the images under high or low stre
Conditions Studied
Interventions
- BEHAVIORAL Acute stress manipulation
Study Locations (1)
California
- University of California, Irvine - Irvine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2025-01-28 |
| Est. Completion | 2028-06-30 |
| Phase | NA |
What NCT06821178 shows while recruiting
NCT06821178 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Stress and Memory in Adolescence appearing as the primary indexed condition, and to 1 intervention - of which Acute stress manipulation is the first listed.
NCT06821178 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06821178 about?
NCT06821178 is a clinical study titled "My Life and My Experiences Project". Child maltreatment is one of the most formidable public health crises in the United States, affecting millions of youth each year. The adverse consequences of maltreatment for youth, as well as for their families and entire communities, are pervasive, costly, and enduring. To intervene and reduce th...
What is the current status of trial NCT06821178?
This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2025-01-28. Estimated completion is 2028-06-30.
What conditions does trial NCT06821178 study?
This clinical trial studies the following conditions: Stress and Memory in Adolescence.
What interventions are being tested in trial NCT06821178?
The interventions under investigation include: Acute stress manipulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06821178?
This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06821178 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06821178's enrollment target sits among peer trials
400 246th of 2000 higher than 1,735 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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