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NCT03731351 · ClinicalTrials.gov registry record
Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)
A clinical trial, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- 20
- Enrollment target
NCT03731351 is a clinical trial that has completed, run by The Cleveland Clinic. The registered enrollment target is 20 participants.
The verdict
NCT03731351 has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
Study Summary
Stroke remains the leading cause of disability in the United States. An estimated 40-50% of all ischemic strokes are caused by large-vessel occlusion of a major cerebral artery (LVO). However, in some cases, the occlusion results in mild symptoms, at least initially, and these patients frequently do not receive any treatment. These strokes, however, may result in unfavorable long-term outcomes despite relatively benign initial course. Recent large randomized studies in patients with severe stroke symptoms and associated LVO showed efficacy and safety of endovascular mechanical thrombectomy, but patients with mild symptoms were not specifically addressed. Based on the investigators' own data and limited evidence in the literature, the investigators propose that early mechanical thrombectomy in patients with LVO associated with mild stroke symptoms (defined as NIHSS ≤ 5) is safe, and results in favorable long-term patient outcomes. The objective of this prospective pilot study is to assess the safety and outcomes of mechanical thrombectomy in patients presenting with acute ischemic stroke due to a large vessel occlusion in the anterior or posterior circulation under 24 hours with mild symptoms (NIHSS ≤ 5).
Interventions
- PROCEDURE Mechanical Thrombectomy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2016-08-03 |
| Est. Completion | 2018-12-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03731351
The ClinicalTrials.gov registry entry for NCT03731351 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Mechanical Thrombectomy is the first listed.
NCT03731351 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03731351 about?
NCT03731351 is a clinical study titled "Mild Acute Ischemic Stroke With Large Vessel Occlusion (MISTWAVE)". Stroke remains the leading cause of disability in the United States. An estimated 40-50% of all ischemic strokes are caused by large-vessel occlusion of a major cerebral artery (LVO). However, in some cases, the occlusion results in mild symptoms, at least initially, and these patients frequently do...
What is the current status of trial NCT03731351?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2016-08-03. Estimated completion is 2018-12-01.
What interventions are being tested in trial NCT03731351?
The interventions under investigation include: Mechanical Thrombectomy (PROCEDURE).
Who is sponsoring clinical trial NCT03731351?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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