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NCT01737554 · ClinicalTrials.gov registry record

Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents

A clinical trial of Cancer and Hematologic Disorders, sponsored by St. Jude Children's Research Hospital.

Completed
Registry status
10
Enrollment target
1
Study location

NCT01737554: Completed study of Cancer and Hematologic Disorders, sponsored by St. Jude Children's Research Hospital.

NCT01737554 is a study of Cancer and Hematologic Disorders that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 10 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01737554, a study of Cancer and Hematologic Disorders, has completed, sponsored by St. Jude Children's Research Hospital.

COMPLETED
Registry status
10 participants
Enrollment target
1
Study location

Study Summary

Catheter occlusion and dysfunction are common complications of central venous access device (CVAD) use in children with cancer and hematologic disorders. These events can lead to interruption of therapy and may require device removal and replacement. Attempts to clear occlusion can cause device fracture. There is a clear link between catheter occlusion and other serious complications including bloodstream infection and intravascular thrombosis. There is evidence that catheter occlusion or dysfunction may be preceded by subclinical catheter narrowing, which could be detected by accurate measurement of catheter resistance. This study aims to observe and describe the feasibility and results of catheter resistance monitoring (CRM) over time with the aim of prospectively identifying patients at high risk of catheter occlusion. If CRM is feasible and proves to be sensitive and specific, it could provide an opportunity for preemptive therapy to prevent occlusion, which might also prevent bloodstream infection or thrombosis.

Primary Outcome

To describe the feasibility of CRM in children and adolescents treated at St. Jude, the proportion of attended CRM visits which produce usable resistance data for all lumens of the CVAD will be recorded for each participant, and summary statistics, including median, range and standard deviation will be reported for the study population.

Interventions

  • OTHER Catheter Resistance Monitoring

Study Locations (1)

Tennessee

  • St. Jude Children's Research Hospital - Memphis

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2012-12
Est. Completion 2016-09

What the finished NCT01737554 record still lists

NCT01737554 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower).

The record links to 2 conditions, with Cancer appearing as the primary indexed condition, and to 1 intervention - of which Catheter Resistance Monitoring is the first listed.

NCT01737554 reports a single indexed study location in Tennessee.

Frequently Asked Questions

What is clinical trial NCT01737554 about?

NCT01737554 is a clinical study titled "Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents". Catheter occlusion and dysfunction are common complications of central venous access device (CVAD) use in children with cancer and hematologic disorders. These events can lead to interruption of therapy and may require device removal and replacement. Attempts to clear occlusion can cause device frac...

What is the current status of trial NCT01737554?

This trial is currently completed. The enrollment target is 10 participants. The study started on 2012-12. Estimated completion is 2016-09.

What conditions does trial NCT01737554 study?

This clinical trial studies the following conditions: Cancer, Hematologic Disorders.

What interventions are being tested in trial NCT01737554?

The interventions under investigation include: Catheter Resistance Monitoring (OTHER).

Who is sponsoring clinical trial NCT01737554?

This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01737554 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01737554's enrollment target sits among peer trials

10 601st of 615 higher than 10 of 615 other Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01737554, the US trial registry maintained by the National Library of Medicine. NCT01737554 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.