Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits in the top decile of US sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count).

523 total trials 69 currently recruiting 301 completed early-phase tilt top decile by trial count

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: 523 sponsored US clinical trials, 69 recruiting.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Top-decile sponsor footprint

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ranks in the top decile of sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 20/100

301 of 415 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (72.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

523 total, page 4 of 11

COMPLETED Early Phase 1

Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression

NCT03507608

COMPLETED Phase 1

Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)

NCT03792516

COMPLETED Phase 1

Safety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer

NCT02405221

COMPLETED Phase 1

Test-Retest Reproducibility of 18F-DCFPyL PET/CT in the Evaluation of Patients With Metastatic Prostate Cancer

NCT03793543

TERMINATED Phase 1

Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma

NCT03707457

TERMINATED NA

Automated Method for Breast Cancer Detection

NCT03863522

COMPLETED Phase 2

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

NCT03642067

COMPLETED Phase 1

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

NCT03711058

COMPLETED Early Phase 1

Evaluation of PSMA-based PET as an Imaging Biomarker in Prostate Cancer

NCT02420977

TERMINATED Phase 1

Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas

NCT02659800

TERMINATED Phase 3

Muscadine Plus (MPX) In Men With Prostate Cancer

NCT03535675

COMPLETED NA

Pathologic and Immunologic Response After Ablative Radiation in Lung Cancer

NCT03603002

COMPLETED

Resiliency in Older Adults Undergoing Bone Marrow Transplant

NCT04188678

COMPLETED Early Phase 1

Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the Pancreas

NCT03153410

COMPLETED Phase 2

Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations

NCT03413995

COMPLETED Phase 2

COMbination of Bipolar Androgen Therapy and Nivolumab

NCT03554317

TERMINATED

Skeletal Metastasis Registry

NCT05058014

TERMINATED Phase 1

Idelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies

NCT03151057

COMPLETED Phase 1

A Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cancer

NCT03535727

COMPLETED NA

Cancer, Obesity/Overweight and Insomnia Study

NCT03542604

COMPLETED NA

Radiopaque Hydrogel in Patients Undergoing Radiotherapy for Pancreatic Cancer

NCT03307564

TERMINATED

A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas

NCT03593993

COMPLETED Phase 1

Feasibility and Efficacy of Neoadjuvant Cabozantinib Plus Nivolumab (CaboNivo) Followed by Definitive Resection for Patients With Locally Advanced Hepatocellular Carcinoma (HCC)

NCT03299946

TERMINATED NA

Radiosurgical Hypophysectomy for Bone Metasteses Pain

NCT03377517

COMPLETED Phase 1

Terameprocol in Treating Patients With Recurrent High Grade Glioma

NCT02575794

COMPLETED Phase 1

Clinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian Cancer

NCT03246074

TERMINATED Phase 2

Nivolumab With Ipilimumab in Subjects With Neuroendocrine Tumors

NCT03420521

COMPLETED Phase 2

GVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable Pancreatic Cancer

NCT03161379

COMPLETED Phase 2

Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas Cancer

NCT03006302

COMPLETED Phase 2

Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)

NCT04098068

COMPLETED Phase 2

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

NCT03190265

COMPLETED NA

Transcranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive Function

NCT03487601

TERMINATED Phase 2

Neoadjuvant Immunoradiation for Resectable Non-Small Cell Lung Cancer

NCT03237377

COMPLETED

Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy

NCT03909464

COMPLETED Phase 2

A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma

NCT03250273

COMPLETED Early Phase 1

5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme

NCT03291990

TERMINATED Phase 2

MEDI-551 as Maintenance Therapy After Allogeneic Stem Cell Transplant in Multiple Myeloma

NCT03218163

COMPLETED NA

Assessing the Acceptability of the Use of a Mobile Health App Among Young Adult Female Survivors of Childhood Cancer

NCT03242200

COMPLETED Phase 2

HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma

NCT03216499

TERMINATED Phase 2

Study of Stereotactic Radiotherapy for Breast Cancer

NCT03043794

COMPLETED NA

Involving Family to Improve Communication in Breast Cancer Care

NCT03283553

COMPLETED Phase 2

Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer

NCT02981524

TERMINATED Phase 2

Pembrolizumab in Patients With Leptomeningeal Disease

NCT03091478

TERMINATED Early Phase 1

Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma

NCT02212574

TERMINATED Phase 1

Cohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin

NCT03043989

COMPLETED NA

Post-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery

NCT03711916

COMPLETED Phase 1

Trial of Mistletoe Extract in Patients With Advanced Solid Tumors

NCT03051477

COMPLETED Phase 2

A Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy

NCT03043807

TERMINATED Phase 1

Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer

NCT02995330

TERMINATED Phase 1

Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

NCT02749708

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What is open in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline

69 recruiting of 523 indexed (13% open); 301 completed (58%).

Phase mix: 5 late (III/IV) vs 395 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: open-pipeline peers nationwide

Peers matched on 523 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20%25% Total trials Recruiting share Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsAbbVieBoehringer IngelheimGilead SciencesH. Lee Moffitt Cancer Center and Research InstituteMetroHealth Medical CenterTexas Tech University Health Sciences CenterChiesi Farmaceutici S.p.A.Dizal Pharmaceuticals
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 523 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins page

523 registered trials is a research-attention snapshot, not an endorsement of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins or any single study.

  • 69 of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline card: 523 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.