Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits in the top decile of US sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count).

523 total trials 69 currently recruiting 301 completed early-phase tilt top decile by trial count

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: 523 sponsored US clinical trials, 69 recruiting.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Top-decile sponsor footprint

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ranks in the top decile of sponsors by registered trial count (#69 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 20/100

301 of 415 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (72.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

523 total, page 3 of 11

ACTIVE NOT RECRUITING Phase 2

Pertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer

NCT01937117

ACTIVE NOT RECRUITING NA

MRI for Assessing Prostate Cancer Response

NCT01607008

ACTIVE NOT RECRUITING Phase 2

Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer

NCT01088789

ACTIVE NOT RECRUITING

Johns Hopkins Breast Cancer Program Longitudinal Repository

NCT01937039

ACTIVE NOT RECRUITING Phase 2

Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast Cancer

NCT00616967

NOT YET RECRUITING Phase 1

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

NCT07430202

NOT YET RECRUITING Phase 2

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

NCT07580339

NOT YET RECRUITING Phase 2

PSMA-High: EBRT/ PSMA617/ ADT vs. EBRT/ ADT

NCT07550517

TERMINATED Phase 2

177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma

NCT06322576

TERMINATED NA

Surgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma

NCT06122480

TERMINATED Phase 2

Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer

NCT05501548

TERMINATED Phase 1

RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis

NCT05298358

COMPLETED Phase 1

Post-transplant Flotetuzumab for AML

NCT05506956

TERMINATED NA

SMART-ER: Symptom Monitoring With Patient-reported Outcomes

NCT05560685

TERMINATED Phase 2

Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma

NCT05025423

COMPLETED Phase 2

Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer

NCT05081193

TERMINATED NA

Combined Aerobic and Resistance Exercise Training in Metastatic Renal Cell Carcinoma

NCT05103722

COMPLETED Phase 2

Durvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma

NCT04301778

COMPLETED

HPV in Sinonasal Ca: Retrospective Analysis Association of Human Papilloma Virus (HPV) Serology and Behavioral Risk Factors

NCT04979000

TERMINATED

Incidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to Apixaban

NCT04895553

COMPLETED Phase 1

Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor

NCT04465643

TERMINATED NA

Breath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) Patients

NCT04843306

COMPLETED Phase 3

Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery

NCT04117074

COMPLETED Phase 2

Adaptive Nutrition and Exercise Weight Loss (A-NEW) Study

NCT04499950

TERMINATED Phase 1

Camostat With Bicalutamide for COVID-19

NCT04652765

TERMINATED Phase 1

[18F]FLOR (FC303) PET/CT Imaging in Patients With Prostate Cancer

NCT04528199

TERMINATED Phase 1

PET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)

NCT04524195

COMPLETED Phase 2

Plerixafor and Cemiplimab in Metastatic Pancreatic Cancer

NCT04177810

COMPLETED

Improving Cancer On-treatment Symptom Management

NCT04589247

COMPLETED NA

TheraSphere® For Treatment of Metastases in Liver

NCT04517643

COMPLETED Phase 2

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

NCT03914794

COMPLETED NA

Behavioral Weight Loss Program for Cancer Survivors in Maryland

NCT04534309

COMPLETED Phase 2

INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancer

NCT04116073

COMPLETED NA

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431

COMPLETED NA

Observation of Perioperative Outcomes of Robotic Pancreaticoduodenectomy

NCT04171440

COMPLETED Phase 1

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

NCT03914742

COMPLETED Phase 2

Nivolumab in Biochemically Recurrent dMMR Prostate Cancer

NCT04019964

TERMINATED Early Phase 1

AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery

NCT03965494

COMPLETED Phase 1

Trial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreatic Ductal Adenocarcinomas.

NCT03767582

TERMINATED Phase 1

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

NCT03971734

TERMINATED Phase 1

Assessment of Multi-Modality Quantitative Imaging for Evaluation of Response of Metastatic Prostate Cancer to Therapy

NCT03619655

COMPLETED NA

Combined Technology Enhanced Home Exercise Program and Other Non-pharmacological Intervention for Cancer Survivors

NCT03576274

COMPLETED Phase 2

CTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stage of HCC (Hepatocellular Carcinoma) Using Durvalumab and Tremelimumab

NCT03638141

TERMINATED Phase 2

Allogeneic Myeloma GM-CSF Vaccine With Lenalidomide in Multiple Myeloma Patients in Complete or Near Complete Remission

NCT03376477

TERMINATED Phase 2

Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer

NCT03886493

COMPLETED Phase 2

RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers

NCT04037358

COMPLETED NA

Tailored Home-Based Exercise Program for Multiple Chronic Conditions

NCT03874754

TERMINATED Phase 2

Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG

NCT03973918

COMPLETED Phase 2

Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN

NCT03878979

TERMINATED Phase 1

A Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients With Resectable Solid Tumor Malignancies

NCT03471286

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What is open in the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline

69 recruiting of 523 indexed (13% open); 301 completed (58%).

Phase mix: 5 late (III/IV) vs 395 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins: open-pipeline peers nationwide

Peers matched on 523 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 0%5%10%15%20%25% Total trials Recruiting share Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsAbbVieBoehringer IngelheimGilead SciencesH. Lee Moffitt Cancer Center and Research InstituteMetroHealth Medical CenterTexas Tech University Health Sciences CenterChiesi Farmaceutici S.p.A.Dizal Pharmaceuticals
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 523 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins page

523 registered trials is a research-attention snapshot, not an endorsement of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins or any single study.

  • 69 of Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins pipeline card: 523 registered trials from official public datasets.Report a data error.