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NCT03711058 · ClinicalTrials.gov registry record · Phase 1

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

A Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 1
Development phase
48
Enrollment target

NCT03711058 is a Phase 1 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 48 participants.

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The verdict

NCT03711058, a Phase 1 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 1
Development phase
48 participants
Enrollment target

Study Summary

A phase I/II study of PI3Kinase inhibition (copanlisib) and anti-PD-1 antibody nivolumab in relapsed/refractory solid tumors with expansions in mismatch-repair proficient (MSS) colorectal cancer.

Interventions

  • DRUG Nivolumab
  • DRUG Copanlisib

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2019-01-17
Est. Completion 2025-06-30
Phase Phase 1

What the Registry Record Tells You About NCT03711058

The ClinicalTrials.gov registry entry for NCT03711058 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Nivolumab is the first listed.

NCT03711058 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03711058 about?

NCT03711058 is a clinical study titled "Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer". A phase I/II study of PI3Kinase inhibition (copanlisib) and anti-PD-1 antibody nivolumab in relapsed/refractory solid tumors with expansions in mismatch-repair proficient (MSS) colorectal cancer.

What is the current status of trial NCT03711058?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2019-01-17. Estimated completion is 2025-06-30.

What interventions are being tested in trial NCT03711058?

The interventions under investigation include: Nivolumab (DRUG), Copanlisib (DRUG).

Who is sponsoring clinical trial NCT03711058?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.