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NCT03291990 · ClinicalTrials.gov registry record · Early Phase 1
5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme
A Early Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 3
- Enrollment target
NCT03291990: Completed Early Phase 1 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
NCT03291990 is a Early Phase 1 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 3 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03291990, a Early Phase 1 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 3 participants
- Enrollment target
Study Summary
This investigation is not only to develop an improved radiation/temozolomide approach, but also develop a regimen with potential to form the basis of better combined therapy with immune based treatments.
Primary Outcome
To measure the incidence of \> grade 3ymphopenia resulting from combined stereotactic hypofractionated radiotherapy and standard temozolomide in malignant glioma at the the standard follow-up 10 weeks after the initiation of therapy.
Interventions
- DRUG Temozolomide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2017-10-18 |
| Est. Completion | 2020-08-19 |
| Phase | Early Phase 1 |
What the finished NCT03291990 record still lists
NCT03291990 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Temozolomide is the first listed.
NCT03291990 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03291990 about?
NCT03291990 is a clinical study titled "5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme". This investigation is not only to develop an improved radiation/temozolomide approach, but also develop a regimen with potential to form the basis of better combined therapy with immune based treatments.
What is the current status of trial NCT03291990?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 3 participants. The study started on 2017-10-18. Estimated completion is 2020-08-19.
What interventions are being tested in trial NCT03291990?
The interventions under investigation include: Temozolomide (DRUG).
Who is sponsoring clinical trial NCT03291990?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03291990's enrollment target sits among peer trials
3 1949th of 2000 higher than 28 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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