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NCT03153410 · ClinicalTrials.gov registry record · Early Phase 1

Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the Pancreas

A Early Phase 1 study of Pancreatic Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Early Phase 1
Development phase
11
Enrollment target
1
Study location

NCT03153410 is a Early Phase 1 study of Pancreatic Cancer that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 11 participants, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03153410, a Early Phase 1 study of Pancreatic Cancer, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Early Phase 1
Development phase
11 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate whether combining cyclophosphamide (CY), pembrolizumab, GVAX and IMC-CS4 is effective and safe in patients with borderline resectable pancreatic cancer.

Conditions Studied

Interventions

  • DRUG Pembrolizumab
  • DRUG Cyclophosphamide
  • DRUG GVAX Pancreas Vaccine (GVAX)
  • DRUG IMC-CS4

Study Locations (1)

Maryland

  • Sidney Kimmel Comprehensive Cancer Center - Baltimore

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2018-09-27
Est. Completion 2023-08-29
Phase Early Phase 1

What the Registry Record Tells You About NCT03153410

The ClinicalTrials.gov registry entry for NCT03153410 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 393-participant average among 278 other Pancreatic Cancer trials with a reported enrollment target (97% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pancreatic Cancer appearing as the primary indexed condition, and to 4 interventions - of which Pembrolizumab is the first listed.

NCT03153410 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT03153410 about?

NCT03153410 is a clinical study titled "Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the Pancreas". The purpose of this study is to evaluate whether combining cyclophosphamide (CY), pembrolizumab, GVAX and IMC-CS4 is effective and safe in patients with borderline resectable pancreatic cancer.

What is the current status of trial NCT03153410?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 11 participants. The study started on 2018-09-27. Estimated completion is 2023-08-29.

What conditions does trial NCT03153410 study?

This clinical trial studies the following conditions: Pancreatic Cancer.

What interventions are being tested in trial NCT03153410?

The interventions under investigation include: Pembrolizumab (DRUG), Cyclophosphamide (DRUG), GVAX Pancreas Vaccine (GVAX) (DRUG), IMC-CS4 (DRUG).

Who is sponsoring clinical trial NCT03153410?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03153410 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.