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NCT03216499 · ClinicalTrials.gov registry record · Phase 2

HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma

A Phase 2 study, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target

NCT03216499 is a Phase 2 study that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 24 participants.

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The verdict

NCT03216499, a Phase 2 study, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target

Study Summary

This phase II trial studies how well HIF-2 alpha inhibitor PT2385 works in treating patients with recurrent glioblastoma. HIF-2 alpha inhibitor PT2385 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • OTHER Laboratory Biomarker Analysis
  • OTHER Pharmacological Study
  • OTHER Pharmacogenomic Study
  • DRUG HIF-2alpha Inhibitor PT2385

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2017-09-14
Est. Completion 2020-06-05
Phase Phase 2

What the Registry Record Tells You About NCT03216499

The ClinicalTrials.gov registry entry for NCT03216499 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Laboratory Biomarker Analysis is the first listed.

NCT03216499 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03216499 about?

NCT03216499 is a clinical study titled "HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma". This phase II trial studies how well HIF-2 alpha inhibitor PT2385 works in treating patients with recurrent glioblastoma. HIF-2 alpha inhibitor PT2385 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

What is the current status of trial NCT03216499?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2017-09-14. Estimated completion is 2020-06-05.

What interventions are being tested in trial NCT03216499?

The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Pharmacological Study (OTHER), Pharmacogenomic Study (OTHER), HIF-2alpha Inhibitor PT2385 (DRUG).

Who is sponsoring clinical trial NCT03216499?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.