Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

523 total trials 69 currently recruiting 301 completed

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins sponsors 523 registered US clinical trials on ClinicalTrials.gov, 69 of them currently recruiting, and 301 completed. 5 of these trials are in Phase 3-4 (later-stage) and 395 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 17 trials.

Trial Pipeline

523 total, page 2 of 11

RECRUITING Phase 1

Intraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pancreatic Adenocarcinoma

NCT05141513

RECRUITING Phase 2

Bipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT04704505

RECRUITING Phase 1

Mutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer

NCT05013216

RECRUITING Phase 1

Study of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell

NCT07062549

RECRUITING Phase 2

Trial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca

NCT04988074

RECRUITING Phase 2

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

NCT04753879

RECRUITING Phase 1

Combination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer

NCT04892303

RECRUITING Phase 1

HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

NCT04131413

RECRUITING Phase 2

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

NCT04363164

RECRUITING Phase 1

DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

NCT04248569

RECRUITING

Proton Radiation Therapy Registry

NCT04376229

RECRUITING Phase 2

Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures

NCT04232085

RECRUITING Phase 2

Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations

NCT03786796

RECRUITING Phase 2

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

NCT03521830

RECRUITING Phase 1

Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

NCT03465592

RECRUITING NA

Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases

NCT03223922

RECRUITING NA

Image-Guided Gynecologic Brachytherapy

NCT02993900

RECRUITING

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

NCT05995821

RECRUITING Phase 2

Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

NCT01804634

ACTIVE NOT RECRUITING Phase 1

Tagraxofusp-erzs, an IL-3 Diphtheria Fusion Protein, in Combination With Gemtuzumab Ozogamicin in Patients With Relapsed/Refractory AML

NCT05716009

ACTIVE NOT RECRUITING Phase 1

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

NCT05823571

ACTIVE NOT RECRUITING Phase 2

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

NCT05014776

ACTIVE NOT RECRUITING NA

Proton Pencil Beam Scanning GRID for Treatment of Bulky Tumors

NCT05121545

ACTIVE NOT RECRUITING Phase 1

Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)

NCT04658147

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca

NCT04848116

ACTIVE NOT RECRUITING

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

NCT04447651

ACTIVE NOT RECRUITING Phase 2

Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma

NCT04209686

ACTIVE NOT RECRUITING Phase 2

Intravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer

NCT04386746

ACTIVE NOT RECRUITING Phase 1

Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer

NCT04117087

ACTIVE NOT RECRUITING Phase 1

Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM

NCT03961971

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma

NCT03918252

ACTIVE NOT RECRUITING Phase 1

Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

NCT03875287

ACTIVE NOT RECRUITING Phase 1

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer

NCT03610711

ACTIVE NOT RECRUITING Phase 2

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

NCT03607890

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer

NCT03573648

ACTIVE NOT RECRUITING Phase 2

Determinants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for HR+ MBC

NCT03439735

ACTIVE NOT RECRUITING Phase 2

Study of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer

NCT03471650

ACTIVE NOT RECRUITING NA

Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins

NCT02965755

ACTIVE NOT RECRUITING Phase 1

A Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance

NCT03114865

ACTIVE NOT RECRUITING Phase 1

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

NCT03044613

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With Muscle-Invasive Urothelial Carcinoma of the Bladder

NCT02845323

ACTIVE NOT RECRUITING Phase 1

Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma

NCT02989636

ACTIVE NOT RECRUITING Phase 2

Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis

NCT03047135

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer

NCT02923180

ACTIVE NOT RECRUITING Phase 2

Palbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase Inhibitor

NCT02738866

ACTIVE NOT RECRUITING

Monitoring Plasma Tumor DNA in Early-Stage Breast Cancer

NCT02743910

ACTIVE NOT RECRUITING Phase 2

Study of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant Prostate Cancer

NCT02452008

ACTIVE NOT RECRUITING Phase 2

Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas

NCT02451982

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC

NCT02259621

ACTIVE NOT RECRUITING Phase 2

Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

NCT02177578

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What the Pipeline for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Shows

According to the ClinicalTrials.gov registry, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is linked to 523 US clinical trials across every stage of research activity. Of those, 69 studies are currently recruiting, about 13% of the sponsor's indexed portfolio, and 301 are already marked complete, representing roughly 58% of the total.

The phase mix for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 395 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is Prostate Cancer with 17 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.