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NCT02177578 · ClinicalTrials.gov registry record · Phase 2
Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
A Phase 2 study of Glioblastoma Multiforme, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Active
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT02177578 is a Phase 2 study of Glioblastoma Multiforme that is active but no longer recruiting, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 60 participants, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (37% lower). The trial reports 3 study locations across 2 states.
The verdict
NCT02177578, a Phase 2 study of Glioblastoma Multiforme, is active but no longer recruiting, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
In this study patients will be treated with 6 weeks of radiation therapy plus temozolomide chemotherapy according to the standard of care. However, the radiation treatment plan will be modified to deliver an higher than routine radiation dose to the subventricular zone which is an area of the brain that contains stem cells that some scientists believe may contribute to glioblastoma recurrence. The purpose of the study is to see if the tumor is controlled for a longer period of time in patients treated with this modified radiation technique than it is in patients treated with standard radiation therapy plus temozolomide chemotherapy.
Conditions Studied
Interventions
- DRUG Temozolomide
- RADIATION Subventricular Zone radiation
- RADIATION Neural Progenitor Cell Sparing radiation
Study Locations (3)
Maryland
- The SKCCC at Johns Hopkins - Baltimore
- Suburban Hospital - Bethesda
District of Columbia
- Sibley Memorial Hospital - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2014-07-08 |
| Est. Completion | 2027-06 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02177578
The ClinicalTrials.gov registry entry for NCT02177578 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 96-participant average among 88 other Glioblastoma Multiforme trials with a reported enrollment target (37% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Glioblastoma Multiforme appearing as the primary indexed condition, and to 3 interventions - of which Temozolomide is the first listed.
NCT02177578 reports 3 study locations spanning 2 distinct geographic areas - top geographies include Maryland, District of Columbia.
Frequently Asked Questions
What is clinical trial NCT02177578 about?
NCT02177578 is a clinical study titled "Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme". In this study patients will be treated with 6 weeks of radiation therapy plus temozolomide chemotherapy according to the standard of care. However, the radiation treatment plan will be modified to deliver an higher than routine radiation dose to the subventricular zone which is an area of the brain ...
What is the current status of trial NCT02177578?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2014-07-08. Estimated completion is 2027-06.
What conditions does trial NCT02177578 study?
This clinical trial studies the following conditions: Glioblastoma Multiforme.
What interventions are being tested in trial NCT02177578?
The interventions under investigation include: Temozolomide (DRUG), Subventricular Zone radiation (RADIATION), Neural Progenitor Cell Sparing radiation (RADIATION).
Who is sponsoring clinical trial NCT02177578?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02177578 being conducted?
This trial has 3 study locations across District of Columbia, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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