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NCT05995821 · ClinicalTrials.gov registry record
Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
A clinical trial of Lung Cancer and Head and Neck Cancer, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- Recruiting
- Registry status
- 1,250
- Enrollment target
- 1
- Study location
NCT05995821 is a study of Lung Cancer and Head and Neck Cancer that is actively recruiting participants, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 1,250 participants, above the 933-participant average among 409 other Lung Cancer trials with a reported enrollment target (34% higher). The trial reports 1 study location across 1 state.
The verdict
NCT05995821, a study of Lung Cancer and Head and Neck Cancer, is actively recruiting participants, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.
- RECRUITING
- Registry status
- 1,250 participants
- Enrollment target
- 1
- Study location
Study Summary
This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect on the immune system. The goal of this discovery and exploratory study is to: * Understand changes in the immune system associated with various cancer treatments, in order to better design new therapies or tests to predict how these treatments might work. * Identify risk factors for those who go on to develop side effects from immunotherapy. * Identify the molecular features associated with response and resistance to cancer therapies and immunotherapy using integrative genomic and immune repertoire characterization. * Capture and characterize systemic tumor burden by minimally invasive analyses of circulating tumor DNA. Participants may be asked to: * Donate samples of tumor, blood, lymph nodes, white blood cells, mouth cells (buccal smears) scraped from the inside of participant's cheek, urine, saliva, or other tissue samples. * Complete questionnaires about immunotherapy side effects at baseline and with follow-up appointments. * Undergo knee x-rays. * Allow the use of demographic and clinical information.
Conditions Studied
Interventions
- OTHER Collection of biological specimens
Study Locations (1)
Maryland
- Johns Hopkins University - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,250 participants |
| Start Date | 2016-08-25 |
| Est. Completion | 2026-08-25 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05995821
The ClinicalTrials.gov registry entry for NCT05995821 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,250 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 933-participant average among 409 other Lung Cancer trials with a reported enrollment target (34% higher). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Lung Cancer appearing as the primary indexed condition, and to 1 intervention - of which Collection of biological specimens is the first listed.
NCT05995821 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT05995821 about?
NCT05995821 is a clinical study titled "Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies". This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect on the immune system. The goal of this discovery and exploratory study is to: * Understand changes...
What is the current status of trial NCT05995821?
This trial is currently recruiting. The enrollment target is 1,250 participants. The study started on 2016-08-25. Estimated completion is 2026-08-25.
What conditions does trial NCT05995821 study?
This clinical trial studies the following conditions: Lung Cancer, Head and Neck Cancer, Gastrointestinal Cancer.
What interventions are being tested in trial NCT05995821?
The interventions under investigation include: Collection of biological specimens (OTHER).
Who is sponsoring clinical trial NCT05995821?
This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05995821 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.